A0A0D2YD52 · A0A0D2YD52_FUSOF

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Confers resistance to H2O2 in hyphae. May play an antioxidative role in fungal defense against the host-produced H2O2 (oxidative burst) at the early stage of plant infection.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per monomer.

Features

Showing features for site, active site, binding site.

TypeIDPosition(s)Description
Site127Transition state stabilizer
Active site131Proton acceptor
Binding site304Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentextracellular region
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      28955419
    • Synonyms
      katG

Organism names

Accessions

  • Primary accession
    A0A0D2YD52

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, cross-link.

TypeIDPosition(s)Description
Signal1-18
ChainPRO_501059385319-781Catalase-peroxidase
Cross-link130↔263Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with Met-289)
Cross-link263↔289Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-130)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Keywords

Interaction

Subunit

Homodimer; disulfide-linked.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    781
  • Mass (Da)
    85,717
  • Last updated
    2015-04-29 v1
  • Checksum
    02ABB334D21110C1
MHVQSLLLASGLVPLAASQGCPFAKRATDNNLVPPREIPEDFGICRVASNQAGGGTRSKDFWPCALRLDVLRQFSPQYSPLGADFDYTEAFKSLDYESLKKDLKALLTDSQDWWPADHGSYGGLFIRMSWHSAGTYRAMDGRGGAGMGQQRFAPLDSWPDNQNLDKARRLLWPIKQKYGSKISWADLVVLAGNVALEHSGFETLGFAGGRADTWEADESIYWGAESTFVPKGNDVRYNGSTDIYERADKLEKPLGATHFGLIYVNPEGPDGSSDPKASALDIRTAFGRMGMDDEETAALIIGGHTLGKTHGAVSSKNIGPEPMAADLGGMGLGWHNSVNEGNGPDQMTSGLEVIWSTTPTKWSNHFLKSLLGNNWTLVESPAGHKQWEALDGKLEYPDPFVKGKFRRPTMLTSDLALINDPAYLKICKRWHDHPKEMNQAFARAWYKLLHRDLGPVSRYLGPEVAKEKFIWQDPLPERKGDIISEGDISSLKSAILSTDGLTVSKLVSTAWNSASTFRGTDKRGGANGARIALEPQVNWASNNPKQLKQVLSALKKVQKNFNSKSSSKQVSLADLIVLGGVAAVEKAAQDAGFKDVKVPFTPGRVAATQNQTDLVQFGYLEPLADGFRNYGHGTARARTEEILVDRAALLTLTPPEMTVLVGGLRALNANYDGSSNGILTEKKGQLTNDFFVNLLSPAFVWTKKDDRGELWTGTDRATKSAKWTATRADLVFGSHAELRAISEVYGSADAKEKFVKDFISAWTKVMNLDRFDVKTEKETKY

Keywords

Genome annotation databases

Similar Proteins

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