A0A0D2Y4S8 · A0A0D2Y4S8_FUSOF

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Note: Binds 1 [3Fe-4S] cluster.

Pathway

Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD+ route): step 1/1.
Energy metabolism; nitrogen metabolism.
Nitrogen metabolism.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site54For GATase activity
Binding site1184[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1190[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1195[3Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionFMN binding
Molecular Functionglutamate synthase (NADH) activity
Molecular Functioniron ion binding
Biological Processglutamine metabolic process
Biological ProcessL-glutamate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    glutamate synthase (NADH)
  • EC number

Gene names

    • Name
      28952693
    • ORF names
      FOXB_06187

Organism names

Accessions

  • Primary accession
    A0A0D2Y4S8
  • Secondary accessions
    • F9FIF8

Proteomes

Organism-specific databases

PTM/Processing

Proteomic databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain54-463Glutamine amidotransferase type-2
Region961-982Disordered

Sequence similarities

Belongs to the glutamate synthase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,113
  • Mass (Da)
    233,588
  • Last updated
    2015-04-29 v1
  • Checksum
    B3B315EAA17C07E8
MGLNEDFDDRQIQTEAEQQPYIPYEYQTENNDSWAGALPVKQGLYDPSYEKDACGVGFACHIKGKPSHKIVSDARNLLCNMTHRGAVGSDARDGDGAGVMTSIPHRFFIKNFEKEEDIKLPPLGQYAVGNLFFKPDEETLQESKRQLEDVAESLGLRVLGWRRPPVDSTLLGPAAKSREPIIAQPFVVLASAYGTGNAPEMTDPEKFDERLFERQLYILRKRATQSIGLHNWFYLCSLSNKNIVYKGQLAPVQVYSYYHDLVNADYEAHFALVHSRFSTNTFPSWDRAQPLRWAAHNGEINTLRGNKNWMRAREGVMQSDIFKEELEQMYPVVEDGGSDSAAFDNVLELLTINGVLSLPEAVMLMVPEAWQGNQHMDPKKAAFYEWAACQMEPWDGPALFTFADGRYCGANLDRNGLRPCRFYVMDDDRIICASEVGTIPVEPETVIQKGRLQPGRMLLVDTQAGRIIDDKELKEAVSSRYDFRAWLDSELITLPKVVEIMEQALDLAPKLDDKAIQADPLLLSYGYTHEQVSLLLAPMAADEKEALGSMGNDAPLACLTQAPRLLYDYFRQLFAQVTNPPIDPIRESIVMSLECYVGPQGNLLEMDASQCGRLLLPSPILSIEEFNAVKNMSNKYSDWTVKTIDLTFPKNQGVQGYIKHLDEICNEASAAIEARDRVIVLSDRNTSADRVPVSAVLASAMVHHHLVSNKWRSMVALVVETAEAREVHHMCVLLGYGADAINPYLAMECILKLNREGLIKKKTTNETLIRNYKHSCDGGILKVMSKMGISTLASYKGAQIFEILGLDETVVERCFRGTASRIQGMTFELIAEEAFRFHERGFPTRETILPSGLPESGEYHWRDGGEPHVNDPTSIANIQDAVRTKNDKSYEAYSRSEYEQIKNCTLRGLLDFKFEDCTPVPIDQVEPWTDIVRRFCTGAMSYGSISMESHSTLAVAMNRLGGKSNTGEGGEDPERSQRMPNGDTMRSAIKQVASGRFGVTSAYLADSDELQIKMAQGAKPGEGGELPGHKVSKSIARTRHSTPGVGLISPPPHHDIYSIEDLKQLIYDLKCSSPRSRVSVKLVSEVGVGIVASGVAKAKADHILISGHDGGTGASRWTGIKYAGLPWELGLAETHQTLVLNDLRGRVVVQTDGQLKTGRDVALACLLGAEEWGFATAPLIAMGCVFMRKCHLNTCPVGIATQDPELRKKFTGTPEHVINFFYYVANELRAIMAQLGFRTINEMVGHVEVLKMRDDLRTNKTANIDLSLLLTPAHKLRPGVATFNVRKQDHKLHVRLDNKLISESELTLDKGLPSRIECDIVNTDRAMGTSLSYHISKRYGEAGLPMDTVHVNIKGSAGQSFGAFLAPGVTLELEGDANDYVGKGLSGGRLIIYPPRSAVFKSEENILIGNTCLYGATTGTCFFRGVAAERFAVRNSGATAVVEGVGDHGCEYMTGGRVVVLGSTGRNFAAGMSGGIAYILDVHGDFHSKLNGEMVEASGLEDPAEIAFVRGLIEDHHHYTGSERAARILVDFNRALPRFIKILPVDYKRVLEEEAAKAAEAKRAEYNLPAVSGVQHKKSEKVAKLQDLEEAVGDNAAEKKRALVLDKTRGFKMYKRRQEKYRPVNSRLKDWAELSSRLDEDELKYQSARCMDCGVPFCQSETGCPISNIIPKWNELVFQNQWKDALNRLLMTNNFPEFTGRVCPAPCEGACVLGINEDPVGIKSIECAIIDRGFEMGWMVPQPPKVRTGKTVAIIGSGPAGLAAADQLNRAGHLVTVYERADRLGGLLMYGIPNMKLDKRIVKRRTDFMASEGIIFKTGVAVGEEGHPSLNDLRASNSAVVIATGATVARDLPIKGRQLEGIHYAMEFLHKNTKSLLDSELADNTYISAKGKDVVVIGGGDTGNDCIGTSLRHGAKSVTNFELLPQPPPERANDNPWPQWPRIYRVDYGHTEVRQHTGKDPREYCIMSEEFMDDGSGKVKGINTIRVEWTKSPSGGWDMKKVEGSQQFFPADLVLLAMGFLGPEARVLGDEIEKDARKNVKTAPGKYSTNLEGVFAAGDARRGQSLIVWGINEGRQAAREIDLYLEKYTNLPVTGGITKRTAQEIFSQIKVEA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AFQF01001867
EMBL· GenBank· DDBJ
EGU83336.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp