A0A0D2XQG4 · A0A0D2XQG4_FUSOF

Function

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for active site, binding site.

148750100150200250300350400450
TypeIDPosition(s)Description
Active site285Proton acceptor
Binding site293Zn2+ (UniProtKB | ChEBI)
Binding site296Zn2+ (UniProtKB | ChEBI)
Binding site317Zn2+ (UniProtKB | ChEBI)
Binding site320Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromosome, subtelomeric region
Cellular Componentmating-type region heterochromatin
Cellular Componentnucleus
Cellular Componentpericentric heterochromatin
Cellular ComponentrDNA heterochromatin
Molecular Functionhistone H3K14 deacetylase activity
Molecular Functionhistone H3K4 deacetylase activity
Molecular Functionmetal ion binding
Molecular FunctionNAD+ binding
Molecular FunctionNAD-dependent histone H3K9 deacetylase activity
Molecular FunctionNAD-dependent histone H4K16 deacetylase activity
Molecular Functiontransferase activity
Biological Processnegative regulation of transcription by RNA polymerase II
Biological ProcesssiRNA-independent facultative heterochromatin formation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Deacetylase sirtuin-type domain-containing protein

Gene names

    • Name
      28948117

Organism names

Accessions

  • Primary accession
    A0A0D2XQG4

Proteomes

Organism-specific databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain157-454Deacetylase sirtuin-type

Sequence similarities

Belongs to the sirtuin family. Class I subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    487
  • Mass (Da)
    54,592
  • Last updated
    2015-04-29 v1
  • Checksum
    F20FF1B4F1F44E70
MHTKKGNGRTVALSKRKAQPNALDKLGDNPTEDEIKTAEANVALAELEERVADVRESWETDSLFEDAFDELNADNTVAINDPKVCTPEEASRLRRELREYGPTVFCQRTVDAGHYTARKLLSAFGIRPPPFLEGQPDDAYFSLLSLAITRELSKRAKLLRHNTVDDAVDLITKSNNIILITGAGISTSLGIPDFRSKGTGLYSKLEHLGLSDPQEVFDIGVFRQDPTIFYSVAKDILPSTDRYTPTHKFIAMLHEKGKLLTNYSQNIDNLEVKAGVPKDKLIQCHGSFGTATCVQCGYKCPGEAIFPEIKADKIPRCPRCIQTLRTTGGAPKRKRSAGTEKKRRRWSADSSDESEYDIPSAGVMKPDITFFGEALPDEFSRRLTEHDRDKVDLVIVIGTSLKVTPVSEIVSWLPAHIPQIYVSRQAVNHINFDIDLLGDCDVVVSELCRRLRWPMVHDMVPKNQKVEVRTEPGYKSRHVFEEQKTKK

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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