A0A0D2XCC1 · A0A0D2XCC1_FUSOF

Function

function

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site70-75FAD (UniProtKB | ChEBI)
Binding site93-108FAD (UniProtKB | ChEBI)
Binding site277FAD (UniProtKB | ChEBI)
Binding site298substrate
Binding site310substrate
Active site342Proton acceptor
Binding site409substrate
Binding site443FAD (UniProtKB | ChEBI)
Binding site454substrate
Binding site459-460FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular Functionelectron transfer activity
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionsuccinate dehydrogenase (quinone) activity
Biological Processmitochondrial electron transport, succinate to ubiquinone
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • EC number

Gene names

    • Name
      28943787

Organism names

Accessions

  • Primary accession
    A0A0D2XCC1

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Peripheral membrane protein
Mitochondrion inner membrane
; Peripheral membrane protein

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue101Tele-8alpha-FAD histidine

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain65-460FAD-dependent oxidoreductase 2 FAD binding
Domain515-650Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal
Region586-605Disordered
Compositional bias587-600Basic and acidic residues

Sequence similarities

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    650
  • Mass (Da)
    71,145
  • Last updated
    2015-04-29 v1
  • MD5 Checksum
    3E78C012795F926D5846F2B703CB7CF9
MMASSMAMRRLAVGPAFTRAARFPSRAFSTTRPVARVITGNGPLRAKEASPFVSNKYAVIDHEYDALVVGAGGAGLRAAFGLAEAGFNTACISKLFPTRSHTVAAQGGINAALGNMHEDDWRWHMYDTVKGSDWLGDQDAIHYMTREAPASIIELENYGCPFSRTEDGKIYQRAFGGQSKQYGKGGQAYRCCAAADRTGHALLHTLYGQSLRHKTNYFIEYFALDLIMQDGECRGVLAYNQEDGTLHRFLANHTVLATGGYGRAYFSCTSAHTCTGDGMAMVARAGLPNQDLEFVQFHPTGIYGAGCLITEGSRGEGGYLLNSEGERFMERYAPTAKDLASRDVVSRSMTMEIREGRGVGAEKDHIYLQLSHLPAEILAERLPGISETAGIFAGVDVRKQPIPVLPTVHYNMGGIPTRYTGEVLTVDEKGEDKVVPGLYACGEAACVSVHGANRLGANSLLDLVVFGRAVSHTIRDKFNPGDALKPVAADAASDHIEVLDKVRTADGPKSTAEIRLAMQKAMQTDVSVFRTQESLDEGVRKMKEIDGMYSQVGMKDRSMIWNSDLVETLELRNLLTCAIQTATSAANRKESRGAHAREDFPERDDENWMKHTLSFQKEPHGKVDLAYRKVIANTLDEAECKPVPPFKRVY

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias587-600Basic and acidic residues

Keywords

Genome annotation databases

Similar Proteins

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