A0A0D2DC68 · A0A0D2DC68_9EURO

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site264Mg2+ 1 (UniProtKB | ChEBI)
Binding site264Mg2+ 2 (UniProtKB | ChEBI)
Binding site268Mg2+ 1 (UniProtKB | ChEBI)
Binding site300Mg2+ 2 (UniProtKB | ChEBI)
Binding site304Mg2+ 2 (UniProtKB | ChEBI)
Binding site326substrate

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionisomerase activity
Molecular Functionketol-acid reductoisomerase activity
Molecular Functionmetal ion binding
Biological Processisoleucine biosynthetic process
Biological Processvaline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ketol-acid reductoisomerase, mitochondrial
  • EC number
  • Alternative names
    • Acetohydroxy-acid reductoisomerase
    • Alpha-keto-beta-hydroxylacyl reductoisomerase

Gene names

    • ORF names
      Z517_11990

Organism names

  • Taxonomic identifier
  • Strain
    • CBS 271.37
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Chaetothyriomycetidae > Chaetothyriales > Herpotrichiellaceae > Fonsecaea

Accessions

  • Primary accession
    A0A0D2DC68

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain65-255KARI N-terminal Rossmann
Domain256-403KARI C-terminal knotted

Sequence similarities

Belongs to the ketol-acid reductoisomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    404
  • Mass (Da)
    44,954
  • Last updated
    2015-04-29 v1
  • Checksum
    66F130534E3C0D4C
MASKNFARTLRTASKQKISAPAVQRRSIATALATRPVVAAAQRPAFAAPAQQQKRGVKTIDFAGTKETVFEREDWPREKLLDYFKNDTLALIGYGSQGHGQGLNLRDNGLNVIIGVRKNGASWKEAEQDGWIPGKNLFEVDEAIDRGTIIMNLLSDAAQSETWPAIKPKLTKGKTLYFSHGFSPVFKDLTKVDVPKDIDVILVAPKGSGRTVRSLFREGRGINSSVAVYQDVTGKAEEKAIALGVAIGSGYLYKTTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLRERGHSPSEAFNETVEEATQSLYPLIGANGMDWMYAACSTTARRGAIDWSSKFKDTLKPLFNQLYDSVRDGTETKRSLEFNSAPDYREKYEKEMQDIRDLEIWRAGKAVRSLRPENQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KN846976
EMBL· GenBank· DDBJ
KIW75216.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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