A0A0D2DAI0 · A0A0D2DAI0_9EURO

Function

function

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G2/M (By similarity).
May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).
Has a specific role in chromosome segregation during meiosis II

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular FunctionDNA helicase activity
Molecular Functionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Biological Processestablishment of sister chromatid cohesion
Biological Processnucleobase-containing compound metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase CHL1
  • EC number
  • Alternative names
    • ATP-dependent DNA helicase chl1
    • Chromosome loss protein 1
    • DNA 5'-3' helicase CHL1

Gene names

    • ORF names
      Z517_11346

Organism names

  • Taxonomic identifier
  • Strain
    • CBS 271.37
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Chaetothyriomycetidae > Chaetothyriales > Herpotrichiellaceae > Fonsecaea

Accessions

  • Primary accession
    A0A0D2DAI0

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain4-414Helicase ATP-binding
Region108-153Disordered

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    835
  • Mass (Da)
    94,774
  • Last updated
    2015-04-29 v1
  • Checksum
    71F0FF0B16E42EC2
MEPTQANFCHPYQPYSIQLDFMRELYRCIEERKVGIFESPTGTGKSLSLICGALTWLRDHEQRALQGLTDGGEPLDWLLEAEKTAQRRELLLEREELELRLSRIRKEEASRRQRQHDAKTSKKPRTKIPNDEGNAPDEDEFTLEDYDSEREETSIANYSTAGLSSSTQALLDKLQGPMRTNVEEQEEKDRLKIIFCSRTHSQLTQFVNELRRVKPPPSLSLEAADFTHKPSLEERVKHLALASRKNLCINSKVAGLSSAFAINEQCLELQKPATPKDKKCPYIPARDDKSKVEDFRDRVVAEVRDIEDTSRLGREMQLCPYYASRAAITMSEVLTLPYPLLLQRSAREALGVSVKNNVVIIDEAHNLMDAIADTFSISLRLSQLEEGARQVTAYAGRFKNRLKGKNRVYVMQVIRLLNSMTDSLRGTLQKTTSTEATITAAQLMAGKGVDQIKPHKLLQYLHESKLCHKVEGYSEMRRDHSDSNQGKGALLQFQNFLIVLMNPDDEGRFFISRHDDEVVVRYTLLDPREHFRQIVQDARSVILAGGTMSPMSDYSDYLFSYLDKDRLRTFSFGHIVPPSHLFAQAVGRGPSGIEFDFRYEMRGSERMIIELGDLVVRVCSIVPDGVVVFFPSYDYLARVVSIWQRLPAPRSVMQALGNVKATFQESKSIAVDQLLQEYAAAVDSGRGGLMLSVVGGKLSEGINFSDKLGRAVIAVGLPFPNANGAEWRAKMEHIEGIRYEYCKSQGKTEAESRAEAKSASRGYYENTCMRAVNQSIGRVIRHRNDYAAILMLDRRFSTERISRKLPAWIHGSMNNSLRDWSDIEKGAEVFFRDKR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KN846976
EMBL· GenBank· DDBJ
KIW74576.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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