A0A0D1I054 · A0A0D1I054_STAAU

  • Protein
    L-lactate dehydrogenase
  • Gene
    ldh2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the conversion of lactate to pyruvate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.

Features

Showing features for binding site, active site.

131950100150200250300
TypeIDPosition(s)Description
Binding site12-17NAD+ (UniProtKB | ChEBI)
Binding site16NAD+ (UniProtKB | ChEBI)
Binding site37NAD+ (UniProtKB | ChEBI)
Binding site42NAD+ (UniProtKB | ChEBI)
Binding site68NAD+ (UniProtKB | ChEBI)
Binding site82-83NAD+ (UniProtKB | ChEBI)
Binding site85substrate
Binding site91substrate
Binding site98NAD+ (UniProtKB | ChEBI)
Binding site104NAD+ (UniProtKB | ChEBI)
Binding site121-123NAD+ (UniProtKB | ChEBI)
Binding site123-126substrate
Binding site146NAD+ (UniProtKB | ChEBI)
Binding site151-154substrate
Active site178Proton acceptor
Binding site231substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-lactate dehydrogenase activity
Biological Processglycolytic process
Biological Processlactate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    L-lactate dehydrogenase
  • EC number
  • Short names
    L-LDH

Gene names

    • Name
      ldh2
    • Synonyms
      ldh
      , ldh2_1
    • ORF names
      ACR74_10380
      , AS572_11440
      , BN1321_420103
      , C0102_06415
      , CNH36_14570
      , CV021_14160
      , E1948_09065
      , E1948_13820
      , EIG96_08185
      , EP54_00200
      , EQ90_02785
      , GO793_03135
      , GO814_09260
      , GO941_08220
      , GO942_11560
      , GQX37_02110
      , GZ164_06955
      , HH313_002727
      , HMPREF3211_01206
      , LB359_07215
      , NCTC13131_00122
      , NCTC5664_01150
      , NCTC6133_03520
      , NCTC7878_00840
      , NCTC7972_02029
      , QU38_16120
      , SAMEA1029512_00127
      , SAMEA1029528_00986
      , SAMEA1029536_01042
      , SAMEA1466929_01368
      , SAMEA1531725_00509
      , SAMEA1531744_01710
      , SAMEA2078260_01230
      , SAMEA2078588_01068
      , SAMEA2080344_00744
      , SAMEA2081063_00836
      , SAMEA4008575_02033
      , SAMEA4552975_01834
      , SAMEA70146418_00113
      , SAMEA70245418_00187

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • CA15
    • M121
    • MRSA_S20
    • SA-120
    • AH1
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus

Accessions

  • Primary accession
    A0A0D1I054
  • Secondary accessions
    • A0A7I0YL39

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue222Phosphotyrosine

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-145Lactate/malate dehydrogenase N-terminal
Domain148-312Lactate/malate dehydrogenase C-terminal

Sequence similarities

Belongs to the LDH/MDH superfamily. LDH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    319
  • Mass (Da)
    34,420
  • Last updated
    2015-04-29 v1
  • Checksum
    7779343BCA8006C4
MKTFGKKVVLIGDGSVGSSYAFAMVTQGVADEFVIIDIAKDKVKADVQDLNHGTVHSPSPVDVKAGEYEDCKDADLVVITAGAPQKPGETRLQLVEKNTKIMKSIVKSVMDSGFDGYFLIAANPVDILTRFVKEYTGLPAERVIGSGTVLDSARLQYLISQELGVAPSSVDASIIGEHGDTELAVWSQANVAGISVYDTLKEQTGSEAKAEEIYVNTRDAAYEIIQAKGSTYYGIALALMRISKAILNNENNVLNVSIQLDGQYGGHKGVYLGVPTLVNQHGAVKIYEMPLSAEEQALFDKSVKTLEDTFDSIKYLLED

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP023391
EMBL· GenBank· DDBJ
ATC72783.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTOE010000001
EMBL· GenBank· DDBJ
CAA4076018.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTPI010000003
EMBL· GenBank· DDBJ
CAA4102235.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTPG010000006
EMBL· GenBank· DDBJ
CAA4128086.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTQT010000005
EMBL· GenBank· DDBJ
CAA4370095.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTWD010000004
EMBL· GenBank· DDBJ
CAA4676995.1
EMBL· GenBank· DDBJ
Genomic DNA
CACUNS010000005
EMBL· GenBank· DDBJ
CAA6068200.1
EMBL· GenBank· DDBJ
Genomic DNA
CACURZ010000003
EMBL· GenBank· DDBJ
CAA6324179.1
EMBL· GenBank· DDBJ
Genomic DNA
CAIGXB010000007
EMBL· GenBank· DDBJ
CAC5801673.1
EMBL· GenBank· DDBJ
Genomic DNA
CAIHOM010000002
EMBL· GenBank· DDBJ
CAC7008290.1
EMBL· GenBank· DDBJ
Genomic DNA
CAIIGD010000001
EMBL· GenBank· DDBJ
CAC8189635.1
EMBL· GenBank· DDBJ
Genomic DNA
CAIIKR010000001
EMBL· GenBank· DDBJ
CAC8491846.1
EMBL· GenBank· DDBJ
Genomic DNA
UAUZ02000001
EMBL· GenBank· DDBJ
CAD7352662.1
EMBL· GenBank· DDBJ
Genomic DNA
CVOQ01000037
EMBL· GenBank· DDBJ
CRI19418.1
EMBL· GenBank· DDBJ
Genomic DNA
JXIG01000630
EMBL· GenBank· DDBJ
KIT95424.1
EMBL· GenBank· DDBJ
Genomic DNA
LALJ01000005
EMBL· GenBank· DDBJ
KMR37719.1
EMBL· GenBank· DDBJ
Genomic DNA
LALQ01000001
EMBL· GenBank· DDBJ
KMR58566.1
EMBL· GenBank· DDBJ
Genomic DNA
LFVK01000007
EMBL· GenBank· DDBJ
KSA76767.1
EMBL· GenBank· DDBJ
Genomic DNA
LRQH01000101
EMBL· GenBank· DDBJ
KXA36562.1
EMBL· GenBank· DDBJ
Genomic DNA
JAIGOF010000011
EMBL· GenBank· DDBJ
MBX8594747.1
EMBL· GenBank· DDBJ
Genomic DNA
JAIUEN010000050
EMBL· GenBank· DDBJ
MCE3362138.1
EMBL· GenBank· DDBJ
Genomic DNA
WPRH01000219
EMBL· GenBank· DDBJ
MVI54852.1
EMBL· GenBank· DDBJ
Genomic DNA
WPTS01000027
EMBL· GenBank· DDBJ
MVK35324.1
EMBL· GenBank· DDBJ
Genomic DNA
WPVZ01000461
EMBL· GenBank· DDBJ
MVL45471.1
EMBL· GenBank· DDBJ
Genomic DNA
WPXC01000030
EMBL· GenBank· DDBJ
MVM11302.1
EMBL· GenBank· DDBJ
Genomic DNA
JAAFMT010000008
EMBL· GenBank· DDBJ
NDR16125.1
EMBL· GenBank· DDBJ
Genomic DNA
JAANEC010000024
EMBL· GenBank· DDBJ
NUY11354.1
EMBL· GenBank· DDBJ
Genomic DNA
LNJK01000008
EMBL· GenBank· DDBJ
OWT14766.1
EMBL· GenBank· DDBJ
Genomic DNA
PGWZ01000541
EMBL· GenBank· DDBJ
PPJ70225.1
EMBL· GenBank· DDBJ
Genomic DNA
PKSU01000004
EMBL· GenBank· DDBJ
PZL80443.1
EMBL· GenBank· DDBJ
Genomic DNA
CP038850
EMBL· GenBank· DDBJ
QCT58366.1
EMBL· GenBank· DDBJ
Genomic DNA
CP053070
EMBL· GenBank· DDBJ
QJR08727.1
EMBL· GenBank· DDBJ
Genomic DNA
RQSX01000165
EMBL· GenBank· DDBJ
RZH93163.1
EMBL· GenBank· DDBJ
Genomic DNA
UAUX01000005
EMBL· GenBank· DDBJ
SPZ97443.1
EMBL· GenBank· DDBJ
Genomic DNA
UDJK01000004
EMBL· GenBank· DDBJ
SRC24624.1
EMBL· GenBank· DDBJ
Genomic DNA
UELG01000002
EMBL· GenBank· DDBJ
SRZ64593.1
EMBL· GenBank· DDBJ
Genomic DNA
UHAI01000002
EMBL· GenBank· DDBJ
SUK18479.1
EMBL· GenBank· DDBJ
Genomic DNA
UHAQ01000002
EMBL· GenBank· DDBJ
SUK42496.1
EMBL· GenBank· DDBJ
Genomic DNA
UHAP01000001
EMBL· GenBank· DDBJ
SUK61630.1
EMBL· GenBank· DDBJ
Genomic DNA
UIOA01000010
EMBL· GenBank· DDBJ
SVG10828.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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