A0A0D1H2U8 · A0A0D1H2U8_STAAU

  • Protein
    1,4-dihydroxy-2-naphthoyl-CoA synthase
  • Gene
    menB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

hydrogencarbonate (UniProtKB | Rhea| CHEBI:17544 )

Pathway

Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.
Quinol/quinone metabolism; menaquinone biosynthesis.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site34substrate; ligand shared between two neighboring subunits; in other chain
Binding site73-77substrate; ligand shared between two neighboring subunits; in other chain
Binding site85substrate; ligand shared between two neighboring subunits; in other chain
Site85Important for catalysis
Binding site117-121substrate; ligand shared between two neighboring subunits; in other chain
Binding site142-144hydrogencarbonate (UniProtKB | ChEBI)
Binding site143substrate; ligand shared between two neighboring subunits; in other chain
Binding site149substrate; ligand shared between two neighboring subunits; in other chain
Binding site246substrate; ligand shared between two neighboring subunits
Site246Important for catalysis
Binding site261substrate; ligand shared between two neighboring subunits

GO annotations

AspectTerm
Molecular Function1,4-dihydroxy-2-naphthoyl-CoA synthase activity
Biological Processmenaquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    1,4-dihydroxy-2-naphthoyl-CoA synthase
  • EC number
  • Short names
    DHNA-CoA synthase

Gene names

    • Name
      menB
    • ORF names
      CV021_04760
      , DQV00_13210
      , G0Z31_06955
      , G6W84_04315
      , G6Y24_06145
      , GO793_14635
      , GO941_15705
      , GQX52_12130
      , M1K003_1655
      , NCTC5664_02578
      , NCTC6133_01252
      , QU38_05470
      , SAMEA70153168_01600

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • SA-120
    • M1K003
    • G703N2B1
    • pt061.1
    • Pt061.1
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus

Accessions

  • Primary accession
    A0A0D1H2U8
  • Secondary accessions
    • A0A2P7DZI1

Proteomes

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region254-273Disordered

Sequence similarities

Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    273
  • Mass (Da)
    30,412
  • Last updated
    2015-04-29 v1
  • Checksum
    DE689BC838E41DBE
MTNRQWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAIIGN010000005
EMBL· GenBank· DDBJ
CAC8237822.1
EMBL· GenBank· DDBJ
Genomic DNA
BDVT01000007
EMBL· GenBank· DDBJ
GBV20661.1
EMBL· GenBank· DDBJ
Genomic DNA
JXIG01000623
EMBL· GenBank· DDBJ
KIT97321.1
EMBL· GenBank· DDBJ
Genomic DNA
WPRH01000772
EMBL· GenBank· DDBJ
MVI57082.1
EMBL· GenBank· DDBJ
Genomic DNA
WPVZ01000846
EMBL· GenBank· DDBJ
MVL46884.1
EMBL· GenBank· DDBJ
Genomic DNA
JAAJIY010000017
EMBL· GenBank· DDBJ
NGK21254.1
EMBL· GenBank· DDBJ
Genomic DNA
JAALWO010000006
EMBL· GenBank· DDBJ
NGV46339.1
EMBL· GenBank· DDBJ
Genomic DNA
JAALTR010000170
EMBL· GenBank· DDBJ
NGW67078.1
EMBL· GenBank· DDBJ
Genomic DNA
JAANDN010000108
EMBL· GenBank· DDBJ
NUY69368.1
EMBL· GenBank· DDBJ
Genomic DNA
PGWZ01000326
EMBL· GenBank· DDBJ
PPJ75511.1
EMBL· GenBank· DDBJ
Genomic DNA
UHAP01000001
EMBL· GenBank· DDBJ
SUK39518.1
EMBL· GenBank· DDBJ
Genomic DNA
UHAQ01000003
EMBL· GenBank· DDBJ
SUK84252.1
EMBL· GenBank· DDBJ
Genomic DNA
QNXM01000003
EMBL· GenBank· DDBJ
TXL50575.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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