A0A0C9ZB01 · A0A0C9ZB01_9AGAM
- ProteinKetol-acid reductoisomerase, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids408 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- (2R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (2S)-2-acetolactate + NADPH + H+
Cofactor
Note: Binds 2 magnesium ions per subunit.
Pathway
Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 266 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 266 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 270 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 302 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 306 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 328 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | ketol-acid reductoisomerase activity | |
Molecular Function | metal ion binding | |
Biological Process | isoleucine biosynthetic process | |
Biological Process | valine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameKetol-acid reductoisomerase, mitochondrial
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Boletales > Suillineae > Suillaceae > Suillus
Accessions
- Primary accessionA0A0C9ZB01
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 68-257 | KARI N-terminal Rossmann | |||
Domain | 258-405 | KARI C-terminal knotted | |||
Sequence similarities
Belongs to the ketol-acid reductoisomerase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length408
- Mass (Da)44,731
- Last updated2015-04-29 v1
- ChecksumCC814F4FC9F8BC68
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KN835713 EMBL· GenBank· DDBJ | KIK34720.1 EMBL· GenBank· DDBJ | Genomic DNA |