A0A0C7KHW8 · A0A0C7KHW8_KLEPN
- ProteinUvrABC system protein A
- GeneuvrA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids941 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 31-38 | ATP (UniProtKB | ChEBI) | |||
Binding site | 640-647 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | excinuclease repair complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Molecular Function | excinuclease ABC activity | |
Molecular Function | zinc ion binding | |
Biological Process | nucleotide-excision repair | |
Biological Process | SOS response |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameUvrABC system protein A
- Short namesUvrA protein
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella
Accessions
- Primary accessionA0A0C7KHW8
Proteomes
Subcellular Location
Interaction
Subunit
Forms a heterotetramer with UvrB during the search for lesions.
Structure
Family & Domains
Features
Showing features for zinc finger, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Zinc finger | 253-280 | C4-type | |||
Domain | 607-937 | ABC transporter | |||
Zinc finger | 740-766 | C4-type | |||
Sequence similarities
Belongs to the ABC transporter superfamily. UvrA family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length941
- Mass (Da)103,973
- Last updated2015-04-29 v1
- Checksum02DEAE6FCF763AB8
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAAKYD010000003 EMBL· GenBank· DDBJ | NGN71485.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UKGE01000005 EMBL· GenBank· DDBJ | SXN30376.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
ULCI01000021 EMBL· GenBank· DDBJ | SYR46333.1 EMBL· GenBank· DDBJ | Genomic DNA |