A0A0C6EU92 · A0A0C6EU92_9RICK
- ProteinUDP-N-acetylenolpyruvoylglucosamine reductase
- GenemurB
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids295 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation.
Catalytic activity
- NADP+ + UDP-N-acetyl-alpha-D-muramate = H+ + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine
Cofactor
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 168 | |||||
Sequence: R | ||||||
Active site | 218 | Proton donor | ||||
Sequence: S | ||||||
Active site | 288 | |||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | FAD binding | |
Molecular Function | UDP-N-acetylmuramate dehydrogenase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylenolpyruvoylglucosamine reductase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rickettsiales > Rickettsiaceae
Accessions
- Primary accessionA0A0C6EU92
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 24-188 | FAD-binding PCMH-type | ||||
Sequence: VGGDADIFFKPEDIEDLKTFLKENNNRFPITVIGAGSNLIIRDKGVEGIVIKLGRNFTDIQFIDNNLIVAGAGCLNSNLAKFCLVNSIAGFEFLVGIPGTVGGGVAMNAGSYGREFKDIVASVEVLDTEGNLIIIPVDRIGFSYRTNSLPKDLIFTRVFFQAKNK |
Sequence similarities
Belongs to the MurB family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length295
- Mass (Da)32,462
- Last updated2015-04-29 v1
- Checksum79D55FFF7D3FF4D7