A0A0C5QRX6 · A0A0C5QRX6_APHGO
- ProteinMalate dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids334 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- (S)-malate + NAD+ = oxaloacetate + NADH + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 44 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 94 | substrate | |||
Binding site | 100 | substrate | |||
Binding site | 107 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 131-133 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 133 | substrate | |||
Binding site | 164 | substrate | |||
Active site | 189 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrion | |
Molecular Function | L-malate dehydrogenase (NAD+) activity | |
Biological Process | malate metabolic process | |
Biological Process | NADH metabolic process | |
Biological Process | oxaloacetate metabolic process | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMalate dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Sternorrhyncha > Aphidomorpha > Aphidoidea > Aphididae > Aphidini > Aphis > Aphis
Accessions
- Primary accessionA0A0C5QRX6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 8-154 | Lactate/malate dehydrogenase N-terminal | |||
Domain | 158-330 | Lactate/malate dehydrogenase C-terminal | |||
Sequence similarities
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length334
- Mass (Da)36,208
- Last updated2015-04-29 v1
- MD5 Checksum3EE15E1345B4B13646E5A6A25DEFEB72
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KM609501 EMBL· GenBank· DDBJ | AJQ30125.1 EMBL· GenBank· DDBJ | mRNA | ||
OU899037 EMBL· GenBank· DDBJ | CAH1737283.1 EMBL· GenBank· DDBJ | Genomic DNA |