A0A0C4F0U3 · A0A0C4F0U3_PUCT1

Function

function

Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.

Catalytic activity

  • Release of an N-terminal tripeptide from a polypeptide.
    EC:3.4.14.10 (UniProtKB | ENZYME | Rhea)

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for active site, binding site.

160750100150200250300350400450500550600
Type
IDPosition(s)Description
Active site284Charge relay system
Active site288Charge relay system
Active site506Charge relay system
Binding site548Ca2+ (UniProtKB | ChEBI)
Binding site549Ca2+ (UniProtKB | ChEBI)
Binding site567Ca2+ (UniProtKB | ChEBI)
Binding site569Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functionmetal ion binding
Molecular Functionserine-type endopeptidase activity
Molecular Functiontripeptidyl-peptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tripeptidyl-peptidase II
  • EC number

Organism names

Accessions

  • Primary accession
    A0A0C4F0U3

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-17
ChainPRO_500217174318-607tripeptidyl-peptidase II

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain202-589Peptidase S53

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    607
  • Mass (Da)
    67,150
  • Last updated
    2015-04-01 v1
  • Checksum
    89479730DD17C268
MKLGVLGLIASISSAGGATLRMEDAAQAAPQSSVLFEAHRAPARFQKLREPPRDGHRITLQIGLRNTRFEDSIDGLLERMSDPSHPDFRPHLDDDEFAELVEPDSQSVAAVVGWLESHGFRNDQMKWTARKDWISLERVPLRKVEHMLNTTYSVYQDQDSERIIRTEKYSLPKNLHRHIDLVQPTTMFAQATIKNICLGPILVTNGCLRRLYKTENYQVQVPERNMIATTGYLGESANFEDAQLFLRTQRADQVGGTFDVVLVNGGSNPQDLNQQQIDKQLGVEANLDTQTALGLTLPTRNVFYSVGGRPPFIADLATPENNNEPFLEWLQYMLAQPIEKIPKVISSSYGDEEQSVPFSYARRVCYGFAALSARGVSLIFSSGDYGVGESGTCYTNDGHRKKAFLPDFPASCPYVTTVGGTENFYPEVAASKFGLAGFASGGGFSNYFQRPEWQRNAVDRYLQFLGPDEFKGFYNPAGRAYPDVSAQGSRYAIAWRQTFLSVDGTSASSPTFASIIALLNDYSLSLGGPSLGYLNPWLYASGYRGLNDITLGNARGCNTTGFRAAEGWDPVTGLGTPDFQKLQELIRPWSLAMAQGAKAFRAKIKAI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ADAS01007318
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

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