A0A0C2YPH7 · A0A0C2YPH7_HEBCY

Function

function

Catalyzes the single-oxidation or sequential double oxidation reaction of carbohydrates primarily at carbon-2 and/or carbon-3 with the concomitant reduction of the flavin. The enzyme exhibits a broad sugar substrate specificity, oxidizing different aldopyranoses to the corresponding C-1, C-2, C-3 or C-1,2, C-2,3 and C-3,4 (di)dehydro sugars with substrate-specific regioselectivity. Accepts only a narrow range of electron acceptors such as substituted benzoquinones and complexed metal ions and reacts extremely slowly with O2 as acceptor. May play a role in the natural recycling of plant matter by oxidizing all major monosaccharides in lignocellulose and by reducing quinone compounds or reactive radical species generated during lignin depolymerization.

Catalytic activity

  • a pyranoside + acceptor = a pyranosid-3,4-diulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)
  • a pyranoside + acceptor = a pyranosid-3-ulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)
  • pyranose + acceptor = pyranos-2,3-diulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)
  • pyranose + acceptor = pyranos-2-ulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)
  • pyranose + acceptor = pyranos-3-ulose + reduced acceptor.
    EC:1.1.99.29 (UniProtKB | ENZYME | Rhea)

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site264FAD (UniProtKB | ChEBI)
Active site542Proton donor
Active site586Proton acceptor

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionoxidoreductase activity, acting on CH-OH group of donors

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    pyranose dehydrogenase (acceptor)
  • EC number

Gene names

    • ORF names
      M413DRAFT_392481

Organism names

  • Taxonomic identifier
  • Strain
    • h7
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Hymenogastraceae > Hebeloma

Accessions

  • Primary accession
    A0A0C2YPH7

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_500215951822-607pyranose dehydrogenase (acceptor)

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain35-354Glucose-methanol-choline oxidoreductase N-terminal
Domain459-595Glucose-methanol-choline oxidoreductase C-terminal

Sequence similarities

Belongs to the GMC oxidoreductase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    607
  • Mass (Da)
    64,823
  • Last updated
    2015-04-01 v1
  • MD5 Checksum
    02CA215A10542F647CDF70711D9962BE
MNFSKLLSFVVTSLIVAPSLGATITDASQVASKTFDYVIVGGGTAGLVVASRLTENPNVSVLVLEAGISDEGIFQIQVPFLGPTVLPNTPLDWNYTIVPQAGMNGRTFAYPRGKLLGGSSSANYLFHQYGTDEDWNRLGSVSGDAGWSWSNMKKYVQKHEKFTPPVDGHNTTGQFIPKLHGFNGLTSVSLPGASTPLDPRVINATQTSSEYPFNQDMSGGDHSLLGIGWLQSSAGGGVRSSSSTSYLAPANSRPNLTVLVNATVMKLIQTGTKNGVPSFKSVQFGSSPGTGSTPGGGAPTTVSAKKEVILSAGSVGTTQILQLSGIGNQRDLQAVKIKTIVNSPKVGYNLGDHTLLPNLYNVQPGSSFDDFLRDPNQINDAVNQWVTTKTGRLANNVVNNFGFARLPRNATIFKKNKDPAPGPKSPHWEVIFGNFWFNPGIPQPSTGDFLVVVSVLLNPTSRGTIKLKSNNPFDKPLIDPNYLTTDLDIFTMRESVKSINRFLAEPTLSNYVVSRFGDNFVSADDDSSIDAYVRSLTTTIFHPVGTASISSKNSNNGVVNPDLTVKGADGLRVIDASVFPFVPSSHTQGPVYLLAERASDIIKAAKY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KN831776
EMBL· GenBank· DDBJ
KIM42957.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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