A0A0B7MRI8 · A0A0B7MRI8_9CAUD

Function

function

Baseplate central spike protein

Baseplate central spike complex-associated lysozyme that is essential for the localized hydrolysis of bacterial cell wall, so that the tail tube, through which the phage DNA is ejected, can penetrate to the host inner membrane. The tail lysozyme complex at the tip of the tail tube penetrates through the outer membrane into the periplasm. This way, lysozyme domain is released and locally digests the peptidoglycan layer to make a hole to let the tube penetrate to the inner membrane. Involved in the tail assembly.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

  • Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.
    EC:3.2.1.17 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

159950100150200250300350400450500550
TypeIDPosition(s)Description
Active site189Proton donor
Active site198Nucleophile

GO annotations

AspectTerm
Cellular Componentvirus tail, baseplate
Molecular Functionlysozyme activity
Biological Processcell wall macromolecule catabolic process
Biological Processdefense response to bacterium
Biological Processkilling of cells of another organism
Biological Processpeptidoglycan catabolic process
Biological Processsymbiont entry into host cell via disruption of host cell envelope
Biological Processsymbiont entry into host cell via disruption of host cell wall peptidoglycan
Biological Processviral tail assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Baseplate central spike protein
  • Alternative names
    • Peptidoglycan hydrolase
      (EC:3.2.1.17
      ) . EC:3.2.1.17 (UniProtKB | ENZYME | Rhea)

Gene names

    • ORF names
      BN201_0135

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Krischvirus > Krischvirus gec3s

Accessions

  • Primary accession
    A0A0B7MRI8

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50353485161-599Baseplate central spike protein

Expression

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain33-178Protein Gp5 N-terminal OB-fold

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    599
  • Mass (Da)
    66,231
  • Last updated
    2015-04-01 v1
  • MD5 Checksum
    54774EA0AD6CEC7C009C7441F7B8CD22
MLMFNNSVKWFTGIVENREDPLMLGRVQVRIHGIHPSLSAHGDIQGLPTEDLLWITPVQDITSAAISGIGQSPTGIVEGSMVFGLALDERYLNCVILGTIAGQYTEKPLTTEGFCDPSGAYPRYIGNDVNILARGGINPETGQTTKPDSVYIRDENTGVAVNPDDEPLDQIPVDDNPDFTIEKMLRGDEGYREKWYLDSEGYPTIGIGHLIIYKKTSDLGIINNELSKLVGREVTNGRLTAEEVSKVFADDIEKTRRDMRKHPRIAPVYNKCNASRRMALENMAFQIGVGGLGKFKNSLAAMLAEEWKQAYDGLRQSVWANQTPGRSSRVSKIILTGNLESYGVIAPKKEESISDDPRARLRNARIAAYKTQRAEEDPEAPFTPQDTRIMFKEPKSSYSARYPYNHVYESESGHIIEIDDTPSHERYHRKHPSGTFEETRPDGTRVEKIEGDDYLIVKQGRKVNVKGNLQVVVEGDAQVYYMGNVMQTVDGNVTEFIRGNVNQTVEGTANMHVVGDVTAQLDANLTANVKGNAELMIEGNTTETIKGNYDLTVEGNFNMTVNGTKSDQVNGDWSRNCGASVKDIASGTVKIDGSRIDLG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HE978309
EMBL· GenBank· DDBJ
CEO90738.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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