A0A0B5E823 · A0A0B5E823_9TRYP

  • Protein
    Glyceraldehyde-3-phosphate dehydrogenase
  • Gene
    gGAPDH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.

Features

Showing features for binding site, active site, site.

133950100150200250300
TypeIDPosition(s)Description
Binding site13-14NAD+ (UniProtKB | ChEBI)
Binding site39NAD+ (UniProtKB | ChEBI)
Binding site93NAD+ (UniProtKB | ChEBI)
Binding site135NAD+ (UniProtKB | ChEBI)
Binding site166-168D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Active site167Nucleophile
Site195Activates thiol group during catalysis
Binding site198D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site227-228D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site250D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site336NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Molecular FunctionNAD binding
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glyceraldehyde-3-phosphate dehydrogenase
  • EC number

Gene names

    • Name
      gGAPDH

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Strigomonadinae > Kentomonas

Accessions

  • Primary accession
    A0A0B5E823

Subcellular Location

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-167Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding

Sequence similarities

Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    339
  • Mass (Da)
    36,440
  • Last updated
    2015-04-01 v1
  • Checksum
    F97A78B0760B9746
MAPVKVGINGFGRIGRMVFQSICEENLLGTEIDVVAVVDMSTDAEYFAYQMKYDTVHGKPSYTVEVAKSSPSVKKPDVLVVNGHKILCVKAQRSPADLPWGKLGVDYVIESTGLFTNKAKAEGHLKGGAKKVVISAPASGGAKTIVMGVNQQEYNPSSHNVVSNASCTTNCLAPLVHVLTKEGFGIATGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAQNIIPSTTGAAKAVGMVIPSTKGKLTGMSFRVPTPDVSVVDLTFTATRDTSIQEIDAALKRASKTYMKGILGYTEDELVSTDFINDNRSSIYDSKATLQNNLPGEKRFFKLVSWYDNEWG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KM242073
EMBL· GenBank· DDBJ
AJE63448.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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