A0A0B4LEG2 · A0A0B4LEG2_DROME
- ProteinPOU domain protein
- Genepdm3
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1273 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 1206-1265 | Homeobox | ||||
Sequence: KRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGYEREVIRIWFCNKRQALKNTV |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | |
Biological Process | axon guidance | |
Biological Process | axon target recognition | |
Biological Process | axonogenesis | |
Biological Process | positive regulation of transcription by RNA polymerase II | |
Biological Process | regulation of transcription by RNA polymerase II | |
Biological Process | sensory perception of smell |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended namePOU domain protein
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionA0A0B4LEG2
Proteomes
Organism-specific databases
Subcellular Location
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-20 | Disordered | ||||
Sequence: MAEGCEDSAGAAESTTSQSQ | ||||||
Region | 36-69 | Disordered | ||||
Sequence: AAIGATPGGGSSSGNSSSNIGGNTTNSSNNGSNI | ||||||
Compositional bias | 43-69 | Polar residues | ||||
Sequence: GGGSSSGNSSSNIGGNTTNSSNNGSNI | ||||||
Region | 86-150 | Disordered | ||||
Sequence: SVNNNNANAANNNNNNSSSSNNNNNNNNTKMQAMICNKSSSTNNSSSSSSSSSSCSSSSSSSSSA | ||||||
Region | 222-242 | Disordered | ||||
Sequence: SPCSGAAPASPPSASSNSSSH | ||||||
Region | 261-323 | Disordered | ||||
Sequence: HKIHSPSSSSHAHSLHHHHHHHHHPHHSSRSNNNDDEMEITDGHALLSPPPPSHSHSHSPFDS | ||||||
Compositional bias | 271-288 | Basic residues | ||||
Sequence: HAHSLHHHHHHHHHPHHS | ||||||
Region | 343-388 | Disordered | ||||
Sequence: LANQHSPPPMPLPLPLPMQIDGEEDENEGEGEGEGEAEEQSAEVMR | ||||||
Compositional bias | 363-380 | Acidic residues | ||||
Sequence: DGEEDENEGEGEGEGEAE | ||||||
Region | 422-450 | Disordered | ||||
Sequence: TLQQQQQQQQQHPHPHHGHQHHHHHPATA | ||||||
Region | 475-540 | Disordered | ||||
Sequence: EPVATTGPSVAPTSPTHNGGKSKTAKGGSSGNGSGGSSANSGTSSAQQQQQPDNPSSSSSPHHPLS | ||||||
Compositional bias | 481-540 | Polar residues | ||||
Sequence: GPSVAPTSPTHNGGKSKTAKGGSSGNGSGGSSANSGTSSAQQQQQPDNPSSSSSPHHPLS | ||||||
Compositional bias | 689-704 | Polar residues | ||||
Sequence: AATHQQQQQQQQQQVQ | ||||||
Region | 689-776 | Disordered | ||||
Sequence: AATHQQQQQQQQQQVQQQREREREREREREREREREREQHLGIGHLPHSHLAADLRRSAERSPTAGSPTGGSPGLAAKGPQPPPPGAA | ||||||
Compositional bias | 705-745 | Basic and acidic residues | ||||
Sequence: QQREREREREREREREREREREQHLGIGHLPHSHLAADLRR | ||||||
Region | 831-1003 | Disordered | ||||
Sequence: ELSASTSPPAPPPRHHFGHSLRGSSTVSPKHSPQGRMGGSGGSTTTGMNLSQHHERHDRLERLERQERHERRSHTPTATATRASVSSSSSAGHHGGSLPSGRLSPPSSAPSNSAANSISDRGYTSPLFRTHSPQGHALSLGGSPRLERDYLGNGPSSGTATSTSSCGAPTAAG | ||||||
Compositional bias | 851-880 | Polar residues | ||||
Sequence: LRGSSTVSPKHSPQGRMGGSGGSTTTGMNL | ||||||
Compositional bias | 881-906 | Basic and acidic residues | ||||
Sequence: SQHHERHDRLERLERQERHERRSHTP | ||||||
Compositional bias | 907-962 | Polar residues | ||||
Sequence: TATATRASVSSSSSAGHHGGSLPSGRLSPPSSAPSNSAANSISDRGYTSPLFRTHS | ||||||
Compositional bias | 984-1003 | Polar residues | ||||
Sequence: GPSSGTATSTSSCGAPTAAG | ||||||
Region | 1030-1100 | Disordered | ||||
Sequence: LGAPTATATRASSASPRDDSPGPGPSTSSVSHMQPLKLSPSSRSEPPHLSPNGNDNDNDLLMDSPNEPTIN | ||||||
Domain | 1107-1181 | POU-specific | ||||
Sequence: VDGIDLDEIKEFAKAFKLRRLSLGLTQTQVGQALSVTEGPAYSQSAICRFEKLDITPKSAQKIKPVLERWMKEAE | ||||||
Domain | 1204-1264 | Homeobox | ||||
Sequence: SKKRKRRTSFTPQALELLNAHFERNTHPSGTEITGLAHQLGYEREVIRIWFCNKRQALKNT |
Sequence similarities
Belongs to the POU transcription factor family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,273
- Mass (Da)134,199
- Last updated2015-04-01 v1
- Checksum1BF703A0B1E91E97
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0B4JD55 | A0A0B4JD55_DROME | pdm3 | 1292 | ||
B7YZU0 | B7YZU0_DROME | pdm3 | 1291 | ||
Q7JUR9 | Q7JUR9_DROME | pdm3 | 994 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 43-69 | Polar residues | ||||
Sequence: GGGSSSGNSSSNIGGNTTNSSNNGSNI | ||||||
Compositional bias | 271-288 | Basic residues | ||||
Sequence: HAHSLHHHHHHHHHPHHS | ||||||
Compositional bias | 363-380 | Acidic residues | ||||
Sequence: DGEEDENEGEGEGEGEAE | ||||||
Compositional bias | 481-540 | Polar residues | ||||
Sequence: GPSVAPTSPTHNGGKSKTAKGGSSGNGSGGSSANSGTSSAQQQQQPDNPSSSSSPHHPLS | ||||||
Compositional bias | 689-704 | Polar residues | ||||
Sequence: AATHQQQQQQQQQQVQ | ||||||
Compositional bias | 705-745 | Basic and acidic residues | ||||
Sequence: QQREREREREREREREREREREQHLGIGHLPHSHLAADLRR | ||||||
Compositional bias | 851-880 | Polar residues | ||||
Sequence: LRGSSTVSPKHSPQGRMGGSGGSTTTGMNL | ||||||
Compositional bias | 881-906 | Basic and acidic residues | ||||
Sequence: SQHHERHDRLERLERQERHERRSHTP | ||||||
Compositional bias | 907-962 | Polar residues | ||||
Sequence: TATATRASVSSSSSAGHHGGSLPSGRLSPPSSAPSNSAANSISDRGYTSPLFRTHS | ||||||
Compositional bias | 984-1003 | Polar residues | ||||
Sequence: GPSSGTATSTSSCGAPTAAG |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE013599 EMBL· GenBank· DDBJ | AHN55991.1 EMBL· GenBank· DDBJ | Genomic DNA |