A0A0B4JD53 · A0A0B4JD53_DROME

Function

Cofactor

Protein has several cofactor binding sites:
Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Can bind about 5 Ca2+ ions per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site, active site.

152850100150200250300350400450500
TypeIDPosition(s)Description
Binding site93Zn2+ 2 (UniProtKB | ChEBI); catalytic; in inhibited form
Binding site175Zn2+ 1 (UniProtKB | ChEBI)
Binding site177Zn2+ 1 (UniProtKB | ChEBI)
Binding site182Ca2+ 3 (UniProtKB | ChEBI)
Binding site183Ca2+ 3 (UniProtKB | ChEBI)
Binding site190Zn2+ 1 (UniProtKB | ChEBI)
Binding site197Ca2+ 2 (UniProtKB | ChEBI)
Binding site199Ca2+ 2 (UniProtKB | ChEBI)
Binding site201Zn2+ 1 (UniProtKB | ChEBI)
Binding site203Ca2+ 3 (UniProtKB | ChEBI)
Binding site204Ca2+ 1 (UniProtKB | ChEBI)
Binding site206Ca2+ 1 (UniProtKB | ChEBI)
Binding site206Ca2+ 3 (UniProtKB | ChEBI)
Binding site224Zn2+ 2 (UniProtKB | ChEBI); catalytic
Active site225
Binding site228Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site234Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site242Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site352Ca2+ 4 (UniProtKB | ChEBI)
Binding site354Ca2+ 5 (UniProtKB | ChEBI)
Binding site400Ca2+ 5 (UniProtKB | ChEBI)
Binding site447Ca2+ 4 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentdendrite
Cellular Componentextracellular matrix
Cellular Componentextracellular space
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processadult fat body development
Biological Processbasement membrane disassembly
Biological Processbasement membrane organization
Biological Processcell adhesion
Biological Processcell-cell junction organization
Biological Processcollagen catabolic process
Biological Processdorsal trunk growth, open tracheal system
Biological Processextracellular matrix organization
Biological Processfasciculation of motor neuron axon
Biological Processimaginal disc eversion
Biological Processinstar larval development
Biological Processmolting cycle, chitin-based cuticle
Biological Processopen tracheal system development
Biological Processproteolysis
Biological Processregulation of tube length, open tracheal system
Biological Processtissue regeneration
Biological Processventral cord development
Biological Processwound healing

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Submitted names
    • Matrix metalloproteinase 1, isoform I
      (EC:3.4.24.-
      )
    • Matrix metalloproteinase 1, isoform K

Gene names

    • Name
      Mmp1
    • Synonyms
      Dm1-MMP
      , dm1-MMP
      , Dmel\CG4859
      , dMMP1
      , dmmp1
      , l(2)k04809
      , MMP
      , Mmp 1
      , MMP-1
      , Mmp-1
      , mmp-1
      , MMP1
      , MMp1
      , mmp1
    • ORF names
      CG4859
      , Dmel_CG4859

Organism names

  • Taxonomic identifier
  • Strain
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    A0A0B4JD53

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for signal, chain, modified residue.

TypeIDPosition(s)Description
Signal1-24
ChainPRO_501501784925-528
Modified residue382Phosphotyrosine; by PKDCC

Keywords

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain, repeat.

TypeIDPosition(s)Description
Domain112-269Peptidase metallopeptidase
Repeat302-347Hemopexin
Repeat348-393Hemopexin
Repeat394-443Hemopexin
Repeat444-493Hemopexin

Sequence similarities

Belongs to the peptidase M10A family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    528
  • Mass (Da)
    59,064
  • Last updated
    2015-04-01 v1
  • Checksum
    883BB3CC1D8E67D1
MTNCQSSVFIVVGTLFSIMAAAQSAPVSTTTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRKTSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGFEPVFKLDEDDKAAIQSLYGRKTNQLRPTNVYPATTQRPYSPPKVPLDDSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWPGLPGNIDAAFTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDHLDAAMVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISNWEGVPNNLDAALKYTNGYTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGCKNTPSSTAPQVPSLNPNPNQGILPSWMWGLTNRFF

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9W122Q9W122_DROMEMmp1584
A0A0B4JCU7A0A0B4JCU7_DROMEMmp1542
A0A0B4JDA7A0A0B4JDA7_DROMEMmp1554
A0A0B4K7H5A0A0B4K7H5_DROMEMmp1512
Q8MLN6Q8MLN6_DROMEMmp1541

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE013599
EMBL· GenBank· DDBJ
ADV37249.1
EMBL· GenBank· DDBJ
Genomic DNA
AE013599
EMBL· GenBank· DDBJ
ADV37251.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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