A0A0B4JCQ5 · A0A0B4JCQ5_DROME
- Proteinphosphatidate phosphatase
- GeneLpin
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1088 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Publications for A0A0B4JCQ5
Lipin knockdown in pan-neuron of Drosophila induces reduction of lifespan, deficient locomotive behavior, and abnormal morphology of motor neuron.
- AnnotationLipin knockdown in pan-neuron of Drosophila induces reduction of lifespan deficient locomotive behavior and abnormal morphology of motor neuron.
- SourceFlyBase: FBgn0263593, GeneRif: 35790
The Function of Lipin in the Wing Development of <i>Drosophila melanogaster</i>.
- AnnotationdLipin is involved in DNA replication during normal cell cycle progression in wing development of Drosophila melanogaster.
- SourceFlyBase: FBgn0263593, GeneRif: 35790
Torsins Are Essential Regulators of Cellular Lipid Metabolism.
- CategoriesFunction, Subcellular Location
- SourceFlyBase: FBgn0263593
Drosophila Lipin interacts with insulin and TOR signaling pathways in the control of growth and lipid metabolism.
- Annotationdata show that dLipin is subject to intricate control by the insulin and TORC1 pathways and that the cellular status of dLipin impacts how fat body cells respond to signals relayed through the PI3K-Akt pathway.
- CategoryFunction
- SourceFlyBase: FBgn0263593, GeneRif: 35790
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets.
- CategoriesFunction, Subcellular Location
- SourceFlyBase: FBgn0263593
Synphilin-1 alters metabolic homeostasis in a novel Drosophila obesity model.
- CategoryFunction
- SourceFlyBase: FBgn0263593
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formation.
- CategoryFunction
- SourceFlyBase: FBgn0263593
Overexpression of kermit/dGIPC is associated with lethality in Drosophila melanogaster.
- CategoriesSequences, Phenotypes & Variants
- SourceFlyBase: FBgn0263593
Lipin is a central regulator of adipose tissue development and function in Drosophila melanogaster.
- CategoryFunction
- SourceFlyBase: FBgn0263593
Drosophila melanogaster lipins are tissue-regulated and developmentally regulated and present specific subcellular distributions.
- CategoriesExpression, Subcellular Location
- SourceFlyBase: FBgn0263593