A0A0B4J203 · A0A0B4J203_HUMAN

  • Protein
    Protein kinase domain-containing protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

1849100200300400500600700800
TypeIDPosition(s)Description
Binding site387ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleoplasm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functiontransmembrane receptor protein tyrosine kinase activity
Biological Processcell surface receptor protein tyrosine kinase signaling pathway
Biological ProcessmRNA processing

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein kinase domain-containing protein

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A0B4J203

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Single-pass type I membrane protein
Membrane
; Single-pass type I membrane protein
Nucleus

Keywords

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 1,926 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)14PRIDEPhosphoserine
Modified residue (large scale data)37PRIDEPhosphoserine
Modified residue (large scale data)57PRIDEPhosphoserine
Modified residue (large scale data)62PRIDEPhosphoserine
Modified residue (large scale data)68PRIDEPhosphothreonine
Modified residue (large scale data)85PRIDEPhosphoserine
Modified residue (large scale data)87PRIDEPhosphoserine
Modified residue (large scale data)89PRIDEPhosphoserine
Modified residue (large scale data)112PRIDEPhosphoserine
Modified residue (large scale data)221PRIDEPhosphothreonine
Modified residue (large scale data)244PRIDEPhosphoserine
Modified residue (large scale data)258PRIDEPhosphothreonine
Modified residue (large scale data)259PRIDEPhosphoserine
Modified residue (large scale data)262PRIDEPhosphoserine
Modified residue (large scale data)304PRIDEPhosphoserine
Modified residue (large scale data)522PRIDEPhosphotyrosine
Modified residue (large scale data)527PRIDEPhosphoserine
Modified residue (large scale data)609PRIDEPhosphotyrosine
Modified residue (large scale data)748PRIDEPhosphotyrosine
Modified residue (large scale data)753PRIDEPhosphotyrosine

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-96Disordered
Compositional bias238-292Polar residues
Region238-306Disordered
Domain353-714Protein kinase
Region778-849Disordered
Compositional bias789-804Basic and acidic residues
Compositional bias805-820Polar residues

Sequence similarities

Belongs to the FIP1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    849
  • Mass (Da)
    94,704
  • Last updated
    2015-03-04 v1
  • Checksum
    597527ED06A129FF
MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQLPYDSRWEFPRDGLVLGRVLGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSYVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKNLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMMVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKKSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYIIPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias238-292Polar residues
Compositional bias789-804Basic and acidic residues
Compositional bias805-820Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC058822
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC095040
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC098587
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC098821
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC105384
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC110298
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC110792
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC124017
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC138607
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC138779
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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