A0A0B0NKX2 · A0A0B0NKX2_GOSAR
- ProteinDNA replication licensing factor MCM2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids956 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | MCM complex | |
Cellular Component | THO complex | |
Molecular Function | 3'-5' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | metal ion binding | |
Molecular Function | single-stranded DNA binding | |
Molecular Function | single-stranded DNA helicase activity | |
Biological Process | DNA unwinding involved in DNA replication | |
Biological Process | double-strand break repair via break-induced replication | |
Biological Process | mitotic DNA replication initiation | |
Biological Process | negative regulation of DNA helicase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA replication licensing factor MCM2
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Malvales > Malvaceae > Malvoideae > Gossypium
Accessions
- Primary accessionA0A0B0NKX2
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-101 | Disordered | |||
Compositional bias | 11-29 | Polar residues | |||
Compositional bias | 30-48 | Basic and acidic residues | |||
Compositional bias | 49-66 | Acidic residues | |||
Compositional bias | 67-88 | Basic and acidic residues | |||
Compositional bias | 121-151 | Basic and acidic residues | |||
Region | 121-189 | Disordered | |||
Domain | 495-701 | MCM | |||
Region | 713-733 | Disordered | |||
Compositional bias | 718-733 | Basic and acidic residues | |||
Sequence similarities
Belongs to the MCM family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length956
- Mass (Da)108,381
- Last updated2015-03-04 v1
- ChecksumF9BC33C9FE0F525C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 11-29 | Polar residues | |||
Compositional bias | 30-48 | Basic and acidic residues | |||
Compositional bias | 49-66 | Acidic residues | |||
Compositional bias | 67-88 | Basic and acidic residues | |||
Compositional bias | 121-151 | Basic and acidic residues | |||
Compositional bias | 718-733 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KN399732 EMBL· GenBank· DDBJ | KHG13490.1 EMBL· GenBank· DDBJ | Genomic DNA |