A0A0B0D2X2 · A0A0B0D2X2_9BACI
- ProteinATP-dependent helicase/deoxyribonuclease subunit B
- GeneaddB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1168 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB subunit has 5' -> 3' nuclease activity but not helicase activity.
Miscellaneous
Despite having conserved helicase domains, this subunit does not have helicase activity.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 [4Fe-4S] cluster.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 802 | [4Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 1124 | [4Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 1127 | [4Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 1133 | [4Fe-4S] cluster (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | 5'-3' exonuclease activity | |
Molecular Function | ATP binding | |
Molecular Function | double-stranded DNA binding | |
Molecular Function | helicase activity | |
Molecular Function | metal ion binding | |
Biological Process | double-strand break repair via homologous recombination |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent helicase/deoxyribonuclease subunit B
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Halobacillus
Accessions
- Primary accessionA0A0B0D2X2
Proteomes
Interaction
Subunit
Heterodimer of AddA and AddB.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length1,168
- Mass (Da)135,230
- Last updated2015-03-04 v1
- Checksum025779E8CA0319CB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JRNX01000747 EMBL· GenBank· DDBJ | KHE67119.1 EMBL· GenBank· DDBJ | Genomic DNA |