A0A0B0D2X2 · A0A0B0D2X2_9BACI

  • Protein
    ATP-dependent helicase/deoxyribonuclease subunit B
  • Gene
    addB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB subunit has 5' -> 3' nuclease activity but not helicase activity.

Miscellaneous

Despite having conserved helicase domains, this subunit does not have helicase activity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site802[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1124[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1127[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1133[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Function5'-3' exonuclease activity
Molecular FunctionATP binding
Molecular Functiondouble-stranded DNA binding
Molecular Functionhelicase activity
Molecular Functionmetal ion binding
Biological Processdouble-strand break repair via homologous recombination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent helicase/deoxyribonuclease subunit B
  • EC number
  • Alternative names
    • ATP-dependent helicase/nuclease subunit AddB

Gene names

    • Name
      addB
    • ORF names
      LD39_19175

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BBL2006
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Halobacillus

Accessions

  • Primary accession
    A0A0B0D2X2

Proteomes

Interaction

Subunit

Heterodimer of AddA and AddB.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain283-588UvrD-like helicase C-terminal

Sequence similarities

Belongs to the helicase family. AddB/RexB type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,168
  • Mass (Da)
    135,230
  • Last updated
    2015-03-04 v1
  • Checksum
    025779E8CA0319CB
MGMRLLLGRSGAGKSTRCLEEIETKLKADPKGNSIIYIVPDQMTFQQEYALLKREGIEGSIRAQVFSFSRLAWRVLQDTGGGTKKFITSTGVQMMLRKIVEERTSDWRVFQKAVEKQGFIEQLEGIITEFKRYRITPEDLHLQMNALDQFVHTTSQEQGLRDKLEDLSYIYDRLVDALREQYIDSEDQLQLLASKVPEAAFLEGADIYIDGFHSFTPQEYEVIEALLKKVKTIHVTLTTEKPEDGLNPELDLFHETKETYLKLQELTEEAGETIDGVEVLDHTEGRLEGRPAFLHLEKYFDERPAPPYEGEVPIKVAEAVHPRAEIEGVAQEILRLVREEGYRFKDMAILMREPEVYHSLIETLFDDYDIPVFIDEKRTMLNHAMIELIRSALDVVDGNFRYDAVFRLLKTGFIPATDRTYPLSEDAIDELENYVLEYGIRSRSQWFSDKEWVYQRFRGFEQASQTDDEKEKQDRINAYRNQVRKALEAFDTDMREADTIGQRAEVMYVWLEHLRVPQRLEQWRERYDEAGEIERGREQEQVWDAFLQLLDEIVEMAGEERMSLQLFRNTIESGLESLTFAHVPPSMDHVIVGSVDRSRITGIKAAFLLGVTDGMWPMKPPSDGMISEQERALLAEQGLLLADGSSRQLLDDRFYVYLALTMAKDHLWVSYPLSNEEGKSKVPATLIQRIEELFPYCEDHVLLQDPDDLHEATRFITNPVKTRSALTSQLARYLKGYRMEPVWWSVLNWYIDQEESFGLTNRVLQSLFYQNKPVDLSERTTTKLFEKQHKTSVSRLETYHRCSYQYFARHSLNLEERRTYKLDAPDIGQLFHEALKQITEWVQSEGRDFAQLNQGEANQYAERATYQLAPILQNQILHSSNRYKYIQKKLQSVIARAAFVLSEQARKSQFSPVGLELGFGTGKDEKLPALSLNLPNGYELMLRGRIDRVDKALTEEDMFLRIIDYKSSAKGLSLVDVYYGLSLQMLAYLDVVLSNAERWLGSTASPAGVLYFHVHNPMISGKQMLEDSQIEEEIFKKFKMQGLLLENERIVQMMDTGLEKGHSQIIPAGLKAKGGFYKGSQTADAERFQELNRYIRQLMSQAGTNITDGKVKLDPFQQKQQVACNFCPYRSVCQFDPSLEENEYRKLQEMKDEEVLEKIIQREEDSAW

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JRNX01000747
EMBL· GenBank· DDBJ
KHE67119.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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