A0A0A8WLP8 · A0A0A8WLP8_9BACT

  • Protein
    Biosynthetic arginine decarboxylase
  • Gene
    speA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site282-292substrate
Active site502Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processputrescine biosynthetic process from arginine
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • ORF names
      OR1_00138

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • OR-1
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfuromonadia > Geobacterales > Geobacteraceae > Geobacter

Accessions

  • Primary accession
    A0A0A8WLP8

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue100N6-(pyridoxal phosphate)lysine

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain76-342Orn/DAP/Arg decarboxylase 2 N-terminal
Domain371-448Arginine decarboxylase helical bundle
Domain584-633Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    635
  • Mass (Da)
    71,872
  • Last updated
    2015-03-04 v1
  • Checksum
    2B2C833A13DE793D
MEKWSIADSAKIYNIDNWGSELFSINKKGHVCVHPSPTSKYSIDLRELMNDLIKRKIKPPVLLRFMDILEGRIGAINRAFKSAISENEYPAKYRTFYPIKVNQQRQVVEAITQFGKRYNIGLEVGSKPELVVAISFAAGTNTPIICNGYKDAEFIETVLYATKIGFDITIVVEKLFELEKIIALSKKIGIVPKLGIRVKLSSKGTGKWATSGGEDAKFGLRISELMTAIELLEEEGMLERLKLLHFHIGSQITKIDKIKNALIEGTRIYAEMRKMGVGLEYVDIGGGLGVDYDGTKSSYFSSVNYTVEEYANDVVYQIKNICDEAGVDCPNIISESGRAIVAHYSVLITNALDTNTQSLTPDFEEVLETTEKLSPTVRKLVDIYKSIDRHSLREDYHDTLQLIQEAVSLFNLGYLNLQDRAVAEWLCSRIFKKINGILEKIKPIPDELSNFQLSLRQTYFANFSLFQSIPDSWAIDQLFPIMPIQRLNQKPDVMASIADITCDSDGEITSFVGENGRSKFLPLHKVRKNEDYYIGFFLIGAYQEILGDMHNLFGDTNAVHITFNKKTNYKIDTVINGDAVWESLKYVQYKGPEILKHVRDTLEKSVAHRKVSIEESSHFLELLDKTLLGYTYFGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BAZF01000001
EMBL· GenBank· DDBJ
GAM07869.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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