A0A0A7RRZ9 · A0A0A7RRZ9_9MONO

Function

function

Essential cofactor of the RNA polymerase L that plays a central role in the transcription and replication by forming the polymerase complex with RNA polymerase L and recruiting L to the genomic N-RNA template for RNA synthesis. Plays also a central role in the encapsidation of nascent RNA chains by forming the encapsidation complex with the nucleocapsid protein N (N-P complex). Acts as a chaperone for newly synthesized free N protein, so-called N0, allowing encapsidation of nascent RNA chains during replication. The nucleoprotein protein N prevents excessive phosphorylation of P, which leads to down-regulation of viral transcription/ replication. Participates, together with N, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionRNA binding
Molecular FunctionRNA-dependent RNA polymerase activity
Biological ProcessDNA-templated transcription
Biological Processviral genome replication

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoprotein

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • China/BJ/2014
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales > Paramyxoviridae > Orthoparamyxovirinae > Morbillivirus

Accessions

  • Primary accession
    A0A0A7RRZ9

Proteomes

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain4-312Paramyxovirus structural protein P/V N-terminal
Region21-106Disordered
Compositional bias45-69Polar residues
Region137-173Disordered
Region194-236Disordered
Compositional bias210-226Basic and acidic residues
Compositional bias279-300Polar residues
Region279-302Disordered

Sequence similarities

Belongs to the morbillivirus P protein family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    509
  • Mass (Da)
    54,787
  • Last updated
    2015-03-04 v1
  • Checksum
    54E84EB006D131D0
MAEEQAYHVNKGLECIKSLKASPPDLSTIRDTIESWREGLSPSGRATPNPDTSEGDHQNINQSCSPAIGPNKVYLSPEDNLGFREITGNDCEAGLGGVQREGSNSQVQRYHVYSHGGEEIEGLEDADSLVVQADPPVANVFNGGEDGSDDSDVDSGPDDPGRDTLYDRGSVAGNGIARSTDVEKLEGADIQEVLNSQKGKGGRFKGGKTLRVPEIPDVKHSRPSAQSIKKGTDGNSVSSGTVIECLSISGATQTVPESRWESSEQNASVGSVLKSARSAKTIQGSTQESGTIASLTQPKENDSEYEYEDDLFTEIQDIRASIAKIHDDNKTILSKLDSILLLKGEVDTIKKQISKQNISISTIEGHLSSIMIAIPGFGKDIKDPTSEVELNPDLRPIISRDSGRALAEVLKKPAVDRSQKIGTKANSSSKGQLLKDLQLKPVDKQASSAIGFVPSDHESSRNVIRSIIKSSKLNIDHKDYLLDLLNDVKGSKDLKEFHKMLTAILAKHP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias45-69Polar residues
Compositional bias210-226Basic and acidic residues
Compositional bias279-300Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KP260624
EMBL· GenBank· DDBJ
AJA39809.1
EMBL· GenBank· DDBJ
Viral cRNA

Similar Proteins

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