A0A0A7HHU3 · A0A0A7HHU3_MOBJA

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

Accessions

  • Primary accession
    A0A0A7HHU3

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane21-42Helical
Transmembrane62-81Helical
Transmembrane93-111Helical
Transmembrane117-137Helical
Transmembrane149-168Helical
Transmembrane195-217Helical
Transmembrane224-245Helical
Transmembrane257-274Helical
Transmembrane286-304Helical
Transmembrane310-330Helical
Transmembrane351-370Helical
Transmembrane390-415Helical
Transmembrane436-458Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-110NADH:ubiquinone oxidoreductase chain 4 N-terminal
Domain113-401NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    460
  • Mass (Da)
    51,791
  • Last updated
    2015-03-04 v1
  • MD5 Checksum
    0278F1915C365D323BAC58D76B164158
MLKIIIPTIMLYPISWATPKKWLWVTSISHSLLIAFISLHWFKWNTEVGWDFSNSYLGVDPLSSPLLSLTCWLLPLMLLASQNHLNNEPHTRQRIYINLLITLQLLLIMAFSATEMVLFYIMFEATLIPTLIVITRWGNQTERLNAGTYFLFYTLVGSLPLLVALLILQNDLGSLSMLTLQYPQLMNSASWANKFWWAACLIAFLVKMPLYGAHLWLPKAHVEAPIAGSMILAAILLKLGGYGMMRIMPVLDPLTKNLAFPFLILALWGIIMTSSTCLRQTDLKSMIAYSSVSHMGLVAAAILIQTPWSFAGATALMIAHGLISSTLFCLANTNYERTHTRTLILTRGLQIILPLMATSWFLTNLANLALPPSPNLMGELLIISSLFKWSQWTLIMTGLGVLLTASYSLYMFIMTQRGPLPSHLTFMNPSHTREHTLMYLHLIPTLLLILKPELILGWTS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KM364984
EMBL· GenBank· DDBJ
AIZ03140.1
EMBL· GenBank· DDBJ
Genomic DNA
KM364988
EMBL· GenBank· DDBJ
AIZ03192.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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