A0A0A7GGW3 · A0A0A7GGW3_GEOAI

  • Protein
    DNA polymerase sliding clamp
  • Gene
    pcn
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionDNA binding
Molecular FunctionDNA polymerase processivity factor activity
Biological Processleading strand elongation
Biological Processregulation of DNA replication

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    DNA polymerase sliding clamp
  • Alternative names
    • Proliferating cell nuclear antigen homolog
      (PCNA
      )

Gene names

    • Name
      pcn
    • ORF names
      GACE_2248

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SBH6
  • Taxonomic lineage
    Archaea > Euryarchaeota > Archaeoglobi > Archaeoglobales > Archaeoglobaceae > Geoglobus

Accessions

  • Primary accession
    A0A0A7GGW3

Proteomes

Interaction

Subunit

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-95Proliferating cell nuclear antigen PCNA N-terminal
Domain121-239Proliferating cell nuclear antigen PCNA C-terminal

Sequence similarities

Belongs to the PCNA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    245
  • Mass (Da)
    27,143
  • Last updated
    2015-03-04 v1
  • Checksum
    321C293934030384
MIDVIMDGEVLRAVTRAMVALVSEARFHFQEQGLHSRAVDPANVAMVIVDVSRDNLEAYSIDEEKTVGVDVNRIYDIAKGIKKNELVELKVEDEATLKVKFGSVVYSVALIDPSAIRKEPKIPNLDLPAKIVLDAGEFKKAIASADKISDHVVFRSDSTGFYIEAEGDVDRIVFHMSEAELIEFNRAEARSMFSVEYLKEFIKVAGTGDLLTVHLGTNYPVRLVFEVAGGKAKVEYILAPRIEAE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP009552
EMBL· GenBank· DDBJ
AIY91269.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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