A0A0A7EF61 · A0A0A7EF61_9GAMM

Function

function

Oxidizes proline to glutamate for use as a carbon and nitrogen source.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.
Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site783
Active site817

GO annotations

AspectTerm
Cellular Componentcytoplasmic side of plasma membrane
Molecular Function1-pyrroline-5-carboxylate dehydrogenase activity
Molecular FunctionDNA binding
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionproline dehydrogenase activity
Biological Processproline biosynthetic process
Biological Processproline catabolic process to glutamate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional protein PutA

Including 2 domains:

  • Recommended name
    Proline dehydrogenase
  • EC number
  • Alternative names
    • Proline oxidase
  • Recommended name
    Delta-1-pyrroline-5-carboxylate dehydrogenase
  • EC number
  • Short names
    P5C dehydrogenase
  • Alternative names
    • L-glutamate gamma-semialdehyde dehydrogenase

Gene names

    • Name
      putA
    • ORF names
      OM33_05725

Organism names

  • Taxonomic identifier
  • Strain
    • OCN003
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Pseudoalteromonadaceae > Pseudoalteromonas

Accessions

  • Primary accession
    A0A0A7EF61

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain12-58Proline utilization A proline dehydrogenase N-terminal
Domain67-180Proline dehydrogenase PutA
Domain190-482Proline dehydrogenase
Domain565-1004Aldehyde dehydrogenase
Domain1023-1199Aldehyde dehydrogenase

Sequence similarities

In the C-terminal section; belongs to the aldehyde dehydrogenase family.
In the N-terminal section; belongs to the proline dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,266
  • Mass (Da)
    139,585
  • Last updated
    2015-03-04 v1
  • Checksum
    7E3B022FD1ACF6F6
MLYNGDLTTKCPIRQQIRDFYRIDEDQVIDHILPLAEVGVSARSRAWERARQMVLNIRNDQEGQGGVDALLNEYSLSSEEGVVLMCLAEALLRVPDKETQESLIRDKLANGDWSAHLGNSDSLFVNASSWGLLLTGKMVNYADKNKEEQFGLLKRTMGRIGEPAIRKSVQYAMKIMGKQFVMGTTIEEAVERAKDKEAKGYAYSYDMLGEGARTMEDAERYFNSYKMAIHVIGKAANGRGPIKSPGISVKLSAIHPRYEFTHRERVMEELVPKLKELALTAKQYDINFTVDAEEADRLDISLDIIEAVFSDDALGNWAGFGLAVQAYQKRAIFVIDWLEALCRRVNRKMMVRLVKGAYWDTEVKLSQADGLEDYPVFTRKATTDVSYKACAIKLMKARDVIFPQFATHNAYSAATILELADGNYSNFEFQRLHGMGESLYDQVVTEDRVQCRVYAPVGHHEDLLAYLVRRLLENGANSSFVNAIVDESQPVESLLEDPVEKIQRVRNKRNPQIVLPKDLYGSERQNSKGLDLTNINHITPFKANLDKWVAENLMTHADVPAGHEAVINPANHAEVLGSIRHQDEAEMKALVDTAEAAFQSWSQTPVAERADILRRTADILERHRDELIALCIKEAGKVAQDGVDEVREAVDFCRYYAARAEELAADSRFSPRGVILCISPWNFPLAIFLGQVAAAIATGNSVIAKPAEQTSLVALRTIELMREVGLPENVVQPVIARGSKVGQVIIPDQRVQAVMFTGSTETGTRIAQTLAERGGDQVPLIAETGGQNCMIVDSTALPEQVVDDVVSSGFQSAGQRCSALRVLFVQEEIADKVIKMIKGAMKELHVGDPAYLSTDVGPVIDQKALDALNEHVEYLKDKATLHFECPIPADNEDGHFFFAPRLYEISDLSVLTKEVFGPCVHVIRFKGTEIDNVINQVNSTGFGLTMGIHTRIEERAEYLAKQSRAGNIYVNRNMIGAVVGVQPFGGRGLSGTGPKAGGPTYLTRLVKENAAPENVQATNINLDGEVIADDSHAVERVNQLMVNSIRDEKTWRATSLNDRISVCRQMLAKIAQVEIMDKLADDLTQTIADARSQLDRIEKRLAKGTVLPGPTGESNTIYLEPRGCVVCYADKDTSFNFWVLSIVTAIAAGNTVITVVSDLFHEEALAFREKLIACGVAEGVLQVAKLSELNAALAHPHVAGAVIGSGCERKAHVNEKLAARSGAILPVISAQYYDTLINRLVTEKTVSIDTTASGGNTSLMTLTDED

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP009888
EMBL· GenBank· DDBJ
AIY64696.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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