A0A0A7EB59 · A0A0A7EB59_MEGAM
- ProteinPhosphotransferase
- GeneGK
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids476 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- ATP + D-glucose = ADP + D-glucose 6-phosphate + H+This reaction proceeds in the forward direction.
Pathway
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.
Carbohydrate metabolism; hexose metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | D-glucose binding | |
Molecular Function | glucokinase activity | |
Biological Process | glycolytic process | |
Biological Process | hexose metabolic process | |
Biological Process | intracellular glucose homeostasis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphotransferase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Xenocyprididae > Xenocypridinae > Megalobrama
Accessions
- Primary accessionA0A0A7EB59
Structure
Family & Domains
Features
Showing features for domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 26-225 | Hexokinase N-terminal | ||||
Sequence: VDQILSEFLLSKEELEEVMRRMRREMERGLRVETHDEASVKMLPTYVRSTPEGSEVGDFLALDLGGTNFRVMLVKVGEDEERGWKVETKHHMYSIPEDAMTGTAEMLFDYIAGCISDFLDKHNLKHKKLPLGFTFSFPVRHEDLDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYY | ||||||
Coiled coil | 30-57 | |||||
Sequence: LSEFLLSKEELEEVMRRMRREMERGLRV | ||||||
Domain | 232-465 | Hexokinase C-terminal | ||||
Sequence: VGMIVGTGCNACYMEEMRKVELVEGEEGRMCVNTEWGAFGDNGELEDFRLEYDRVVDETSLNPGHQLYEKLIGGKYMGELVRLVLLKLVNEDLLFNGEASDLLKTRGAFETRFVSQIESDTGDRKQIYNILSSLGILPSELDCDIVRLACESVSTRAAHMCGAGLAGVINQMRERRCQEELKITVGVDGSVYKLHPRFKERFHKLVWEMTPHCEITFIQSEEGSGRGAALISAV |
Sequence similarities
Belongs to the hexokinase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length476
- Mass (Da)53,649
- Last updated2015-03-04 v1
- Checksum197A65D2903711FB