A0A0A7E6D8 · A0A0A7E6D8_HUMAN
- ProteinAminopeptidase
- GeneERAP1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids941 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 353 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 354 | Proton acceptor | |||
Binding site | 357 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 376 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Site | 438 | Transition state stabilizer | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aminopeptidase activity | |
Molecular Function | metallopeptidase activity | |
Molecular Function | zinc ion binding | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAminopeptidase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A0A7E6D8
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-32 | ||||
Chain | PRO_5002038757 | 33-941 | Aminopeptidase | ||
Proteomic databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 60-246 | Aminopeptidase N-like N-terminal | |||
Domain | 281-484 | Peptidase M1 membrane alanine aminopeptidase | |||
Domain | 597-916 | ERAP1-like C-terminal | |||
Sequence similarities
Belongs to the peptidase M1 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length941
- Mass (Da)107,085
- Last updated2015-03-04 v1
- Checksum6D5C5E4864AC0F80
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 941 | ||||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KM357887 EMBL· GenBank· DDBJ | AIY60629.1 EMBL· GenBank· DDBJ | mRNA |