A0A0A7AAX8 · A0A0A7AAX8_9RHAB
- ProteinRNA-directed RNA polymerase L
- GeneL
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2075 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- GTP + H2O = GDP + H+ + phosphate
- a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N7-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine
- a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H+ + S-adenosyl-L-homocysteine
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | host cell cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | hydrolase activity | |
Molecular Function | mRNA 5'-cap (guanine-N7-)-methyltransferase activity | |
Molecular Function | RNA-dependent RNA polymerase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRNA-directed RNA polymerase L
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales > Rhabdoviridae > Alpharhabdovirinae > Perhabdovirus > Perhabdovirus anguilla
Accessions
- Primary accessionA0A0A7AAX8
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 590-776 | RdRp catalytic | ||||
Sequence: VSIANHIDYEKWNNHQRKESNGPVFRVMGQFPGHPSLIEKTHDFFEQSLIYYNGRPDLMQTDGDELQNRTEALVCWNGQKGGLEGLRQKGWSILNLLVIKRESKIRNTKVQTLAQGDNQVVCTQYRIMPTRSTLELQAELEKVKKNNQVIMDAIETGTNKLGLLINNDETIQSADFLTYGKVPIFRG | ||||||
Domain | 1623-1819 | Mononegavirus-type SAM-dependent 2'-O-MTase | ||||
Sequence: RTAQLATGSHYKLRSILVQNRIQVTDALCGGDGSGGIGACVLRQYPFAKLIYNSLFEIQDLDMRGSAPGPPSAIAAMGNMSMRCVNRDSAWKNPSDLSHTSTWEYFQSLMTQHQLRCNLWTFDMEVRSHDISDAIEEQIVANLHLLPKNGTIIYKTYLTKLSDMETTILDRLGGFFKRVSLVSTDATSSHSSEVYAV |
Sequence similarities
Belongs to the rhabdoviridae protein L family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,075
- Mass (Da)236,081
- Last updated2015-03-04 v1
- Checksum44304FCFFB3F210D