A0A0A6YX02 · A0A0A6YX02_MOUSE
- ProteinRagulator complex protein LAMTOR1
- GeneLamtor1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids142 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Publications for A0A0A6YX02
Arterial cyclic stretch regulates Lamtor1 and promotes neointimal hyperplasia via circSlc8a1/miR-20a-5p axis in vein grafts.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1913758
Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1913758
Loss of LAMTOR1 in pancreatic beta‑cells increases glucose‑stimulated insulin secretion in mice.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1913758
Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.
- CategoriesFunction
- SourceMGI: 1913758
UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity.
- CategoriesFunction, Interaction
- SourceMGI: 1913758
Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1913758
TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation.
- CategoriesFunction
- SourceMGI: 1913758
Investigation of LAMTOR1 gene and protein expressions in germinal vesicle and metaphase II oocytes and embryos from 1-cell to blastocyst stage in a mouse model.
- CategoriesExpression, Subcellular Location
- SourceMGI: 1913758
Lamtor1 Is Critically Required for CD4<sup>+</sup> T Cell Proliferation and Regulatory T Cell Suppressive Function.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1913758
Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.
- CategoriesFunction
- SourceMGI: 1913758
Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals.
- CategoriesFunction
- SourceMGI: 1913758
The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.
- CategoriesInteraction
- SourceMGI: 1913758
Ragulator is a GEF for the Rag GTPases that signal amino acid levels to mTORC1.
- CategoriesInteraction
- SourceMGI: 1913758
A conditional knockout resource for the genome-wide study of mouse gene function.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1913758
A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
- CategoriesExpression
- SourceMGI: 1913758
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
- CategoriesFunction, Subcellular Location
- SourceMGI: 1913758