A0A0A3JJK2 · A0A0A3JJK2_9BACI
- ProteinMalate synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids532 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H+
Pathway
Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 165 | Proton acceptor | ||||
Sequence: R | ||||||
Active site | 445 | Proton donor | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | malate synthase activity | |
Biological Process | glyoxylate cycle | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMalate synthase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Lysinibacillus
Accessions
- Primary accessionA0A0A3JJK2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 9-70 | Malate synthase N-terminal | ||||
Sequence: LKIVGEITPQVEQVLTPEAIEFLTQLHEKFNDRRKELLKFRAERQKRLDAGEKLDFLPETKH | ||||||
Domain | 161-406 | Malate synthase TIM barrel | ||||
Sequence: VLLVRPRGLHMIEKNVTVNDEVMSGSLFDFGLYFFHNAKEAIARGTGPYFYLPKLESHLEARWWNEVFVFAQDYIGIPQGTIKATVLIETVTAAFEMNEILYELREHSKGLNCGRWDYIFSFIKRLRNQPEVVLPDRGQVTMTVPFMRAYTQLCVQTCHKRNAPAMGGMAAQIPVKGDDEANAAAFAKVAEDKRREATDGHDGTWVAHPGMVQTAMEQFDAIMKTPNQIDKKREDVSVTADDLLAI | ||||||
Domain | 411-531 | Malate synthase C-terminal | ||||
Sequence: ITEDGLRVNLNVGVQYIASWLRGQGAAPIHNLMEDAATAEISRTQVWQWIRHPKGILEDGRKVTMELVLQVLEEELAKIKEAVGEQAYESGRYAEATELFKTLIEQDEFVEFLTLPGYTKI | ||||||
Coiled coil | 472-499 | |||||
Sequence: KVTMELVLQVLEEELAKIKEAVGEQAYE |
Sequence similarities
Belongs to the malate synthase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length532
- Mass (Da)60,232
- Last updated2015-02-04 v1
- Checksum45041DE5C658FEC3
Keywords
- Technical term