A0A0A2B7M7 · A0A0A2B7M7_PROMR

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 Zn2+ ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site222Zn2+ (UniProtKB | ChEBI)
Binding site289Zn2+ (UniProtKB | ChEBI)
Binding site296Zn2+ (UniProtKB | ChEBI)
Binding site299Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta'
  • EC number
  • Short names
    RNAP subunit beta'
  • Alternative names
    • RNA polymerase subunit beta'
    • Transcriptase subunit beta'

Gene names

    • Name
      rpoC2
    • ORF names
      EV02_1474

Organism names

  • Taxonomic identifier
  • Strain
    • SB
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Prochlorococcaceae > Prochlorococcus

Accessions

  • Primary accession
    A0A0A2B7M7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain11-64RNA polymerase Rpb1
Domain93-171RNA polymerase Rpb1
Domain174-372RNA polymerase Rpb1
Domain1092-1182RNA polymerase Rpb1
Region1266-1340Disordered
Compositional bias1296-1319Polar residues

Sequence similarities

Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,340
  • Mass (Da)
    146,429
  • Last updated
    2015-02-04 v1
  • Checksum
    BA9E3583CADCF8F1
MPALAKTPPSFKNKVVDKKALKNLVSWAYKTHGTAITAAMADNLKDLGFKYATQAAVSISVDDLKVPEAKQDLIGQAEEQISATEECYRLGEITEVERHTKVIDTWTETNERLVDAVKNNFNQNDPLNSVWMMANSGARGNMSQVRQLVGMRGLMANPQGEIIDLPIRTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRLVDVAQDVIVREEDCGTERSIVVAAEDGKFGARLLGRLTAEDIFDAEENLVVPQNTAIDPALSGEIEKASISEVKIRSPLTCEANRSVCRRCYGWALAHNHLVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVSTAESGVVRSKISGKFEFSSKAKVRGYRTPHGVEAKQAEVDFILKIVPQGNNSGKAQKIEVSSGSLLFVDDGEEISSDITVAQITAGAVKKSVEKATKDVICDLAGQVRYDKVIQPKEVTDRQGNITLKAQRLGRLWVLAGDVYNLPPNAKPVISSGKSADEGTVLAEASQSSEFGGQVRLRESIGDSREVQIVTTSMSLTNFKLIEESTHSGQIYNLESSDGTSYRLNISPGNKISNGEVIADLTDERFRTKTGGLVKYAPGLSVKKARSSKNGFEVSQGGTLLWIPQETHEINKDISLLMIEDMKWIEAGTEVVKDIFSQTSGIVTVTQKNDILREITVRNGTFHECDDEEILNRYTEEGNLVNPGEKILDGVDNKEILFVQKLETPKCRGLLLRTVEEFTIPDQADLPQLSHVKQEKGPQLGLKAIQRLTYKDGELIKSVEGVELLRTHLSIESFDATPQMTIDVESIEDENDASINRLNLVILESILVRRDTISDSSHGSTHTELQVNNNQIVKAGDVIATTQILCKEKGLVKLPNVDDDEPIRRLIVVREEDKIKIKINGEGIVKVGDRVVDGDPISASVKSTSCGEIEEISNSSVTLRLGRPYMVSPDSVLHVKDGDLVLRGDGLALLVFERQKTGDIVQGLPRIEELLEARRPRDSAILCKKSGIVQIKQGNDEESVSLSIIENDDLVNEYQLLLGKNIMVSDGQQVKGGESLTDGPINPHELLDCYFNDLKDQKPLIDAARESISKLQRSMVSEVQNVYKSQGVAIDDKHIEVIVRQMTSKVRIEDAGDTTLLPGELIELRQVEDTNQAMAITGGAPAEFTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFSGFVEELSSEAGPHPDILAEESGGYRRAQNLRPDYTVDMPQSPAVSSTAILDDPSDEDLETTRSRHGIDPTSSNFAAFARPNAENQFSEDQLPDPAALEGLQEEGLLSDE

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1296-1319Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JNAS01000002
EMBL· GenBank· DDBJ
KGG08800.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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