A0A0A1H7F6 · A0A0A1H7F6_9BURK

Function

function

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site203-phosphoshikimate (UniProtKB | ChEBI)
Binding site20phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site213-phosphoshikimate (UniProtKB | ChEBI)
Binding site253-phosphoshikimate (UniProtKB | ChEBI)
Binding site91phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site119phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site1673-phosphoshikimate (UniProtKB | ChEBI)
Binding site1683-phosphoshikimate (UniProtKB | ChEBI)
Binding site1693-phosphoshikimate (UniProtKB | ChEBI)
Binding site169phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site2003-phosphoshikimate (UniProtKB | ChEBI)
Active site324Proton acceptor
Binding site3243-phosphoshikimate (UniProtKB | ChEBI)
Binding site3513-phosphoshikimate (UniProtKB | ChEBI)
Binding site355phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site397phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site422phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site483-491ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-phosphoshikimate 1-carboxyvinyltransferase activity
Molecular FunctionATP binding
Molecular FunctionCMP kinase activity
Molecular FunctiondCMP kinase activity
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process
Biological Processpyrimidine nucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    3-phosphoshikimate 1-carboxyvinyltransferase
  • EC number
  • Alternative names
    • 5-enolpyruvylshikimate-3-phosphate synthase
      (EPSP synthase
      ; EPSPS
      )
  • Recommended name
    Cytidylate kinase
  • EC number
  • Short names
    CK
  • Alternative names
    • Cytidine monophosphate kinase
      (CMP kinase
      )

Gene names

    • Name
      aroA
    • Synonyms
      cmk
    • ORF names
      E1O_20580

Organism names

Accessions

  • Primary accession
    A0A0A1H7F6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-431Enolpyruvate transferase
Domain479-693Cytidylate kinase

Sequence similarities

Belongs to the EPSP synthase family.
Belongs to the cytidylate kinase family. Type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    698
  • Mass (Da)
    73,567
  • Last updated
    2015-02-04 v1
  • Checksum
    F2F02F239BC542D1
MRTVEPIARAAGEVRLPGSKSISNRALLLAALAQGATELSGVLDADDTRVMIAALRTLGVAVEVDGDRVRVAGCGGDFPNREADLFLGNAGTAMRPLAAVLAFAGGRYRLDGVARMRERPIGDLVDAVNGMGARVRYAGTPGYPPLQVEPADRGKLVPRVRVRGAVSSQFVTGLLLAAPGYARATAWRSLTIEIDGNLISQPYVAMTIAMMRQFGADVRAPLPGTYVVGPDAYCAPTGRYAVEGDASGASYFLALGAIAGGPVRVRGVGRDSLQGDVAFTTVLEKMGARVAIGDDWIETAGGGTGVDGRFVLQPVDWDCSEIPDAAMTVAVLALFARGTTRLRGIGSWRVKETDRIHAMATELTKLGAEVEFGDDWIAVTAPEQVREAWIDTYDDHRMAMCLSLAAAAGVPVHVRDPGCVAKTYPDYFDRLDALTRTAAGAVAGFSSPGLQRAGAEEPSLPPGRERAGVRVAAPSVPVIAIDGPTASGKGAVAQRVAQELGFACLDSGALYRIVGLLALEQGVGLDDGPALAAVADALTAAEDPAMRLRFADGRITLGARDITEAIRREEVGRAASRIATAGELRTALLALQRAQRRPPGLVADGRDMGTVVFPDASLKVFLIADVRVRAERRYKQLIEKGYPGTLETLLQDLEERDARDRTRDHAPLVAAEGAKILDSTAMTIDAVVAQVLGWYRAG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP014683
EMBL· GenBank· DDBJ
BAP89189.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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