A0A0A0MRH8 · A0A0A0MRH8_HUMAN
- ProteinChromodomain helicase DNA binding protein 1 like
- GeneCHD1L
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids745 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | nucleoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent chromatin remodeler activity | |
Molecular Function | DNA helicase activity | |
Molecular Function | hydrolase activity | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A0A0MRH8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 990 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 8 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 439 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 476 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 477 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 484 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 733 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 736 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 738 | PRIDE | Phosphoserine | ||||
Sequence: S |
Proteomic databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 199-361 | Helicase C-terminal | ||||
Sequence: LLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMDYRGYSYERVDGSVRGEERHLAIKNFGQQPIFVFLLSTRAGGVGMNLTAADTVIFVDSDFNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIEGGHFTLGAQKPAADADLQ | ||||||
Region | 476-502 | Disordered | ||||
Sequence: STKRKRVLSPEELEDRQKKRQEAAAKR | ||||||
Compositional bias | 479-502 | Basic and acidic residues | ||||
Sequence: RKRVLSPEELEDRQKKRQEAAAKR | ||||||
Region | 535-559 | Disordered | ||||
Sequence: LPSEESEPEDLENGEESSAELDYQD | ||||||
Compositional bias | 539-556 | Acidic residues | ||||
Sequence: ESEPEDLENGEESSAELD | ||||||
Domain | 552-745 | Macro | ||||
Sequence: SAELDYQDPDATSLKYVSGDVTHPQAGAEDALIVHCVDDSGHWGRGGLFTALEKRSAEPRKIYELAGKMKDLSLGGVLLFPVDDKESRNKGQDLLALIVAQHRDRSNVLSGIKMAALEEGLKKIFLAAKKKKASVHLPRIGHATKGFNWYGTERLIRKHLAARGIPTYIYYFPRSKSAVLHSQSSSSSSRQLVP |
Sequence similarities
Belongs to the SNF2/RAD54 helicase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length745
- Mass (Da)83,720
- Last updated2019-07-03 v2
- Checksum367D48B1C0896933
Computationally mapped potential isoform sequences
There are 19 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q86WJ1 | CHD1L_HUMAN | CHD1L | 897 | ||
A0A0A0MSH9 | A0A0A0MSH9_HUMAN | CHD1L | 825 | ||
A0A494C1H0 | A0A494C1H0_HUMAN | CHD1L | 192 | ||
A0A494C1H1 | A0A494C1H1_HUMAN | CHD1L | 55 | ||
A0A494C1I3 | A0A494C1I3_HUMAN | CHD1L | 167 | ||
A0A494C1S1 | A0A494C1S1_HUMAN | CHD1L | 117 | ||
A0A494C1P7 | A0A494C1P7_HUMAN | CHD1L | 792 | ||
A0A494C179 | A0A494C179_HUMAN | CHD1L | 516 | ||
A0A494C1F3 | A0A494C1F3_HUMAN | CHD1L | 50 | ||
A0A494C1F7 | A0A494C1F7_HUMAN | CHD1L | 880 | ||
A0A494C0J6 | A0A494C0J6_HUMAN | CHD1L | 365 | ||
A0A494C0F0 | A0A494C0F0_HUMAN | CHD1L | 293 | ||
A0A494C0Q0 | A0A494C0Q0_HUMAN | CHD1L | 163 | ||
A0A494C0M4 | A0A494C0M4_HUMAN | CHD1L | 191 | ||
A0A494C111 | A0A494C111_HUMAN | CHD1L | 204 | ||
A0A494C0B8 | A0A494C0B8_HUMAN | CHD1L | 165 | ||
A0A087WTM4 | A0A087WTM4_HUMAN | CHD1L | 377 | ||
A0A087WWW4 | A0A087WWW4_HUMAN | CHD1L | 82 | ||
A0A087WZM7 | A0A087WZM7_HUMAN | CHD1L | 56 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 479-502 | Basic and acidic residues | ||||
Sequence: RKRVLSPEELEDRQKKRQEAAAKR | ||||||
Compositional bias | 539-556 | Acidic residues | ||||
Sequence: ESEPEDLENGEESSAELD |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC242426 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |