Comprehensive identification of phosphorylation sites in postsynaptic density preparations.Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCMol. Cell. Proteomics 5:914-922 (2006)Cited in99+99+Mapped to99+
Large-scale phosphorylation analysis of mouse liver.Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 104:1488-1493 (2007)Cited in99+99+Mapped to1
Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M.[...], Zhao Y.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCMol. Cell 50:919-930 (2013)Cited in99+99+Mapped to6
Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.Guo A., Gu H., Zhou J., Mulhern D., Wang Y., Lee K.A., Yang V., Aguiar M., Kornhauser J.[...], Comb M.J.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCMol. Cell. Proteomics 13:372-387 (2014)Cited in99+99+Mapped to13
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Histone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress.Meng X.M., Pang Q.Y., Zhou Z.F., Yuan J.H., You L., Feng Q.P., Zhu B.M.View abstractAnnotationHistone methyltransferase MLL4 protects against pressure overload-induced heart failure via a THBS4-mediated protection in ER stress.SourceGeneRif: 381022PubMedEurope PMCPharmacol Res 205:107263-107263 (2024)Mapped to9
KMT2D regulates activation, localization, and integrin expression by T- cells.Potter S.J., Zhang L., Kotliar M., Wu Y., Schafer C., Stefan K., Boukas L., Qu'd D., Bodamer O.[...], Bjornsson H.T.View abstractAnnotationKMT2D regulates activation localization and integrin expression by T-cells.SourceGeneRif: 381022PubMedEurope PMCFront Immunol 15:1341745-1341745 (2024)Mapped to4
PLD2 deletion ameliorates sepsis-induced cardiomyopathy by suppressing cardiomyocyte pyroptosis via the NLRP3/caspase 1/GSDMD pathway.Li J., Teng D., Jia W., Gong L., Dong H., Wang C., Zhang L., Xu B., Wang W.[...], Yang J.View abstractAnnotationPLD2 deletion ameliorates sepsis-induced cardiomyopathy by suppressing cardiomyocyte pyroptosis via the NLRP3/caspase 1/GSDMD pathway.SourceGeneRif: 381022PubMedEurope PMCInflamm Res 73:1033-1046 (2024)Mapped to4
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment.Li J., Chin C.R., Ying H.Y., Meydan C., Teater M.R., Xia M., Farinha P., Takata K., Chu C.S.[...], Melnick A.M.View abstractAnnotationLoss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment.SourceGeneRif: 381022, MGI: 2682319PubMedEurope PMCNat Commun 15:2879-2879 (2024)Mapped to20
KMT2D Deficiency Causes Sensorineural Hearing Loss in Mice and Humans.Kalinousky A.J., Luperchio T.R., Schrode K.M., Harris J.R., Zhang L., DeLeon V.B., Fahrner J.A., Lauer A.M., Bjornsson H.T.View abstractAnnotationKMT2D Deficiency Causes Sensorineural Hearing Loss in Mice and Humans.CategoriesFunctionSourceGeneRif: 381022PubMedEurope PMCGenes (Basel) 15:48-48 (2023)Mapped to10
The dopaminergic D1 receptor modulates the hyperactivity of Bapa mutant mice.de Oliveira-Higa M.A., da Silva Rodrigues P., Sampaio A.C.S., de Camargo Coque A., Kirsten T.B., Massironi S.M.G., Alexandre-Ribeiro S.R., Mori C.M.C., da Silva R.A., Bernardi M.M.View abstractSourceMGI: 2682319PubMedEurope PMCBehav Brain Res 452:114562-114562 (2023)Mapped to12
KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition.Xu J., Zhong A., Zhang S., Chen M., Zhang L., Hang X., Zheng J., Wu B., Deng X.[...], Niu T.View abstractAnnotationKMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition.CategoriesFunctionSourceGeneRif: 381022PubMedEurope PMCAdv Sci (Weinh) 10:e2206098-e2206098 (2023)Mapped to10
KMT2D links TGF-beta signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity.Lu S., Kim H.S., Cao Y., Bedi K., Zhao L., Narayanan I.V., Magnuson B., Gu Y., Yang J.[...], Shi J.View abstractAnnotationKMT2D links TGF-beta signaling to noncanonical activin pathway and regulates pancreatic cancer cell plasticity.CategoriesFunctionSourceGeneRif: 381022PubMedEurope PMCInt J Cancer 153:552-570 (2023)Mapped to4
Restraint of IFN-gamma expression through a distal silencer CNS-28 for tissue homeostasis.Cui K., Chen Z., Cao Y., Liu S., Ren G., Hu G., Fang D., Wei D., Liu C.[...], Zhao K.View abstractCategoriesFunctionSourceMGI: 2682319PubMedEurope PMCImmunity 56:944-958.e6 (2023)Mapped to13
MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.Xie G., Lee J.E., Senft A.D., Park Y.K., Jang Y., Chakraborty S., Thompson J.J., McKernan K., Liu C.[...], Ge K.View abstractAnnotationMLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.CategoriesFunctionSourceGeneRif: 381022, MGI: 2682319PubMedEurope PMCNat Genet 55:693-705 (2023)Mapped to40
Loss of Histone Methyltransferase KMT2D Attenuates Angiogenesis in the Ischemic Heart by Inhibiting the Transcriptional Activation of VEGF-A.Meng X.M., Liu S.B., Deng T., Li D.Y., You L., Hong H., Feng Q.P., Zhu B.M.View abstractAnnotationLoss of Histone Methyltransferase KMT2D Attenuates Angiogenesis in the Ischemic Heart by Inhibiting the Transcriptional Activation of VEGF-A.CategoriesFunctionSourceGeneRif: 381022PubMedEurope PMCJ Cardiovasc Transl Res 16:1032-1049 (2023)Mapped to10
Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.Boileau R.M., Chen K.X., Blelloch R.View abstractAnnotationLoss of MLL3/4 decouples enhancer H3K4 monomethylation H3K27 acetylation and gene activation during embryonic stem cell differentiation.CategoriesFunctionSourceGeneRif: 381022PubMedEurope PMCGenome Biol 24:41-41 (2023)Mapped to11
Lysine methyltransferase Kmt2d regulates naive CD8<sup>+</sup> T cell activation-induced survival.Kim J., Nguyen T., Cifello J., Ahmad R., Zhang Y., Yang Q., Lee J.E., Li X., Kai Y.[...], Weng N.P.View abstractAnnotationLysine methyltransferase Kmt2d regulates naive CD8[+]CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 381022PubMedEurope PMCFront Immunol 13:1095140-1095140 (2022)Mapped to4
Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme.Lewis M.A., Ingham N.J., Chen J., Pearson S., Di Domenico F., Rekhi S., Allen R., Drake M., Willaert A.[...], Steel K.P.View abstractCategoriesFunctionSourceMGI: 2682319PubMedEurope PMCBMC Biol 20:67-67 (2022)Mapped to58
KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.Pang L., Tian H., Gao X., Wang W., Wang X., Zhang Z.View abstractAnnotationKMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.CategoriesFunction, ExpressionSourceGeneRif: 381022, MGI: 2682319PubMedEurope PMCBiosci Rep 41:BSR20211148-BSR20211148 (2021)Mapped to16
Lysine methyltransferase 2D regulates muscle fiber size and muscle cell differentiation.Wright A., Hall A., Daly T., Fontelonga T., Potter S., Schafer C., Lindsley A., Hung C., Bodamer O., Gussoni E.View abstractAnnotationLysine methyltransferase 2D regulates muscle fiber size and muscle cell differentiation.CategoriesPhenotypes & VariantsSourceGeneRif: 381022, MGI: 2682319PubMedEurope PMCFASEB J 35:e21955-e21955 (2021)Mapped to33
Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation.Luperchio T.R., Boukas L., Zhang L., Pilarowski G., Jiang J., Kalinousky A., Hansen K.D., Bjornsson H.T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 2682319PubMedEurope PMCElife 10:e65884-e65884 (2021)Mapped to25