A0A0A0EU91 · A0A0A0EU91_9GAMM

Function

function

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Pathway

Cofactor biosynthesis; biotin biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site18substrate
Active site78Nucleophile
Binding site78-79substrate
Active site204
Active site232
Binding site232substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpimelyl-[acyl-carrier protein] methyl ester esterase activity
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • EC number
  • Alternative names
    • Biotin synthesis protein BioH
    • Carboxylesterase BioH

Gene names

    • Name
      bioH
    • ORF names
      N792_00260

Organism names

Accessions

  • Primary accession
    A0A0A0EU91

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-236AB hydrolase-1

Sequence similarities

Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    259
  • Mass (Da)
    27,681
  • Last updated
    2015-01-07 v1
  • Checksum
    7B840707C4F1ECEF
MHIETRGHGPALGLIHGWAMHGGLFTPLVDRLAEHYTLHLVDLPGHGHARDDDRALEPVALARALVARVPDAVWLGWSLGGQVALRAALDHPDRVRGLVMLAASPRFVRSDDWPHGVGSALFSDFGDALQRDFRGTLDGFLALEALGSSSAQDELRKLRAQAFERGEPSPRALLEGLRLLDTLDLRAELPGLQLPSLWLSGRRDRLVPAGAMPAAAALAPQSRSVVIANAGHAPFLGAADEVAAEIDTFMRTVSAGQPA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AVPS01000001
EMBL· GenBank· DDBJ
KGM52722.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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