A0A099LNR0 · A0A099LNR0_9VIBR

  • Protein
    dTTP/UTP pyrophosphatase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

Type
IDPosition(s)Description
Site14Important for substrate specificity
Active site72Proton acceptor
Site73Important for substrate specificity
Site155Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function8-oxo-(d)RTP hydrolase activity
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • ORF names
      EA26_19065

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ATCC 51183
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Vibrionales > Vibrionaceae > Vibrio

Accessions

  • Primary accession
    A0A099LNR0

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    188
  • Mass (Da)
    20,846
  • Last updated
    2015-01-07 v1
  • MD5 Checksum
    FDB484F1201E286FA4347881B07FD4A5
MNMSHLVLASGSPRRKELLSQLGHDFSLVVPDIAEAKAEHESPAEYVLRLSQEKALAGLALVCTESVVIGSDTVVVCDEQVLEKPQHLDDAKRMLKQLSNRRHQVMTAVTVVTSNKQRSVVVTTEVWFKALTDDEIEQYWQSGEPCDKAGSYGIQGLGGRFVTRIEGSYHAVVGLPLFETDQLLHEFL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JMCG01000002
EMBL· GenBank· DDBJ
KGK09299.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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