A0A099J2I1 · A0A099J2I1_9MICO

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site64substrate
Binding site156substrate
Binding site218substrate
Binding site219-221NAD+ (UniProtKB | ChEBI)
Binding site248substrate
Binding site252substrate
Binding site253NAD+ (UniProtKB | ChEBI)
Binding site282-287NAD+ (UniProtKB | ChEBI)
Binding site284-289NAD+ (UniProtKB | ChEBI)
Binding site305NAD+ (UniProtKB | ChEBI)
Binding site310NAD+ (UniProtKB | ChEBI)
Binding site340NAD+ (UniProtKB | ChEBI)
Binding site409NAD+ (UniProtKB | ChEBI)
Binding site416NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process
Biological ProcessS-adenosylmethionine cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • ORF names
      BJ997_002650
      , GY21_20780

Organism names

  • Taxonomic identifier
  • Strains
    • RuG17
    • DSM 21065
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Cryobacterium

Accessions

  • Primary accession
    A0A099J2I1

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain253-415S-adenosyl-L-homocysteine hydrolase NAD binding

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    495
  • Mass (Da)
    53,317
  • Last updated
    2015-01-07 v1
  • Checksum
    AEEDAD24D9EA85D2
MTVAPPSTSAAFTYKIADLSLAEAGRHQLRLAENEMPGLMALRTEFGDSKPLAGARIAGSLHMTVQTAVLIETLVALGAQVRWASCNIFSTQDDAAAAIAVGPTGTVDAPAGVPVFAWKGETLEEYWWCTTQIFDWSAEAKAAGETWTGPNLILDDGGDATMLVHKGREFEQAKTVPADSAGDSHEYGVILAALRVSLAASADRWTKVAADLLGVTEETTTGVHRLYELFADKSLLFPAINVNDSVTKSKFDNKYGIRHSLPDGLNRATDVLIGGKVVFVAGYGDVGKGAAEALKGQGARVIVSEIDPINALQAAMDGFQVAKLESVVEDVDIFVSGTGNFNVIRTEHMLRMKHLAIIANVGHFDNEIDMAALEVLPGATKVQIKPQVDEWRLPSGRSILVLSEGRLMNLGNATGHPSFVMSNSFTNQVLAQIELYCFTEKYPVGVYVLPKYLDEKVARLHLDALGVELTVLSPEQAAYLGIPVEGPYKVDHYRY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JPXF01000164
EMBL· GenBank· DDBJ
KGJ71638.1
EMBL· GenBank· DDBJ
Genomic DNA
JACHBQ010000001
EMBL· GenBank· DDBJ
MBB5642102.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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