A0A098B407 · A0A098B407_DESHA

Function

function

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

1727100200300400500600700
TypeIDPosition(s)Description
Binding site491Mg2+ (UniProtKB | ChEBI)
Binding site497Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function3'-5'-RNA exonuclease activity
Molecular Functionmagnesium ion binding
Molecular Functionpolyribonucleotide nucleotidyltransferase activity
Molecular FunctionRNA binding
Biological ProcessmRNA catabolic process
Biological ProcessRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyribonucleotide nucleotidyltransferase
  • EC number
  • Alternative names
    • Polynucleotide phosphorylase
      (PNPase
      )

Gene names

    • Name
      pnp
    • ORF names
      AT727_23430
      , DPCES_2719

Organism names

Accessions

  • Primary accession
    A0A098B407

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain627-701S1 motif
Region698-727Disordered
Compositional bias703-727Polar residues

Sequence similarities

Belongs to the polyribonucleotide nucleotidyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    727
  • Mass (Da)
    79,389
  • Last updated
    2015-01-07 v1
  • Checksum
    BBD9507C1B301C7F
MTQEVLERSIQVGGRTMTFQTGKIGKQAGGAIFCRYGDTVVSAFATGSAQPREGIDFFPLTVEFEERLYAAGKIPGGFIKREGRPSEKAILSARLIDRPIRPLFPEGYRNDVQVVAQVMSVDQDCASDITGINAASAALTISNVPFEGPVAAVTVGLIGDEFIINPTVEQSEKSVMHLTVAGTKDAVMMVEAGAQEVPEAQMLEAIMFGHREIQRIAEFIENYRLEALERNLAKPKQEVVMKQMPEEIVQAVKAFAYDKMDQAVRTEEKKAREEAIRQVKEEALAHFAEQYPEDSKTIDKILEDFVHKIVRRLITVEHIRPDGRALDEIRPISVEVGILPRTHGTGLFTRGQTQVLTVATLGAVGDEQILDGLGLEESKRYMHHYNFPPYSVGETRPMRGPGRREIGHGALAERALLPVIPDENDFPYTIRLVSEVLESNGSSSMASVCGSTLSLMDAGVPVKSPVAGIAMGLISEENHIAILSDIQGMEDHDGDMDFKVAGTSQGVTALQMDIKIKGVSREILERALTQAKEGRLFILDKMLSVIEKPRPELSPFAPRIITASIHPDKIREVIGPGGKTIKKIIDETGVKIDIEDDGRVFISAVDGEAGENALKIIQALTQEVEVGRIYNGRVTRIMDFGAFVEVIPGVLGLSGKEGLVHISQLAHGRVEKVEDVVKLGDDILVKATGIDKQGRLNLSRKEALPNPNPSSNPNPNGITANRNPRNS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias703-727Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LK996017
EMBL· GenBank· DDBJ
CDX02606.1
EMBL· GenBank· DDBJ
Genomic DNA
LOCK01000032
EMBL· GenBank· DDBJ
KTE90811.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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