A0A096ZSN8 · A0A096ZSN8_SFSV

Function

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenthost cell endoplasmic reticulum
Cellular Componenthost cell endoplasmic reticulum-Golgi intermediate compartment
Cellular Componenthost cell Golgi apparatus
Molecular Functionmetal ion binding
Molecular FunctionRNA-dependent RNA polymerase activity
Biological ProcessDNA-templated transcription
Biological Processviral RNA genome replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RNA-directed RNA polymerase L
  • EC number
  • Alternative names
    • Large structural protein
    • Replicase
    • Transcriptase

Organism names

Accessions

  • Primary accession
    A0A096ZSN8

Family & Domains

Features

Showing features for coiled coil, domain.

TypeIDPosition(s)Description
Coiled coil360-387
Domain974-1165RdRp catalytic

Sequence similarities

Belongs to the Bunyavirales RNA polymerase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,090
  • Mass (Da)
    238,361
  • Last updated
    2015-01-07 v1
  • Checksum
    AA2B0B1AA2D86761
MNSIIERQEPLGEGFTRRQLTHCSDSLMNAYLPQFVILPDKDGVSIEIDRESFDLNSATGNSMKNERYQFSALPNFVHDFTFGHLTPLTDVPFVSAFGKFRDGYDHLSPDVIFKTTANSFFIVEFTTFRGGERGCRAAANNKLIKYEVACESRSARERLGLFVIAVHRNGIWTNLSLEDTEVNELVFRYRTALDIFEDLKRRYPELSVDNEDLTRAESELRGIVSSIQLDWKKTSSAFPHFKREVIEGFRNFSPDEEYLSRIISGVIDKAQKDLVRETFSGMLGEHEDRFTMNEKECGAILEKSVEGYYTGREFRHTNDCKSTVQIPAWVTTPGQPGKSLDALAELNVDGDGIMASIWSKVAYEAKIEGIERMMDDKEAELEQALEGSLDRPDLRNKYHRVHLSLTANEQAYIAALGVGGKKRKDSPNVTQARARSKLPFSLYHNTRDLESFLNSDDMSLFEHEMGLYSPLTEDLPLRTAAAAIHQPTLIGREGKNEIIQAHQNFMESQFGSWTQMVSLIGAELSASVKQHVKPNHFVIKRLLNSGIYLLIKPTSSRSHIFVSFAVERSRLMYTFCDSHVFRNCEDAGDLLVTDFVSYKLSKITNLCKTNSLAEASFFFWSECYGYNVWEAQNSLQVNTSMSRDISFMTKLSTLTLLEDKSTTEEIQTMLRYVMMEGFVSQPEIPKPQKMCKKFPKVLRTELQVFIMNKVIDSIMRIARCPFTLQKRDGKISWSGMFNPFSGRPTKELQVIISCCYNGYFKNKEEETEPSSLSNLYKKIIELEDQKPDNDNFLGAGDPESPQMHEFSRSYLKKVCDHGKLLLTRVFGQNFKDQIDSSIMREINSITLERLATLKATSNFGESWYVYKDVKDKSYSRDRLLVKMASFAREGKALAIEKFEDCMSIIEERGAMHICLFKKQQHGGLREIYVLGAEERIVQSIIEAIARSIGRFFHSDTLCNPANKMKIPESHGRRARSHCKGPVWTTATSDDARKWNQGHFVTKFAMMLCEFTHPRWHPIIVRGCSMFTNKYMMMNLQFISILDGRKELPVEDEFVQDLFEGYHGNKTLPWVKPGCTYLQTTTGMMQGILHYTSSLLHTLHQEFIRTLSFRIFDMKVREDMSTRVVVDMMQGSDDSAMLCSFPCSDDHLLSKCKVAATICFRVKKLLGIYLAIYPSEKSTQNTDFVLEYNSEFFFHSQHIRPTIRWVAASCSLPEVETLVARQEEASNLMTSISEGGGTFSLSAMIQQSQCTLHYMLMGMGVSDLFSEYKRAILKWRDPGLGFFLLDNPFCAGLGGFRHNLYNAVTKTNLGKVYAYYLRKVVGKSQDDEFNDEERCSVSAGGAIVLSSSLKWGSRKKFQQLRDRLNIPDDWIDQINDNPEVLYRAPKTGAEIILRISEKLHSPGVVSSLSTGNAVCKVMASSVYFLSAAIFEDTGKPEFRPFNESRYSLLQRMMKYEIYEEGDSVTNEDLIFLFPNIEDLSQLNTIVHDRRRIEVIRRQGGREATQTRVVVFDTPQIRMSPEKLVSDKWFATQKSKIGKTGFETEWAKLRQVVKWLDDTPSDTLLKSPLLNHIQIKNFFARMEVRPRTVRVTGAPVKKRSGLSKLSVVIRDNFCRGGYVKGIEDVSGAHRSMWAELIKHLLFCVLQGPFSQDMKIQLIQKTLYDSPVIDLKESDGKTKTNLISIMQRYIHGEKDVLDVIENVGAGIVGGFVVRQKTKVDNGRVLYYGHGIWRGVMDGVQVQIDVDNHIGAPTNIVAVYMARSSVGPWELLRTIKAWAEDQNIRNTDDVSRTSRKGAHYWMHQFKLTASNLQFGAPVIMVEGRMEAIWDRESENLEMTITRSTVNIGIVNEGNERRMNILSYTATDGDLSPEIIDILPSVETGNVLRHYSGRLINAWVYCRELELRDIRRLSKMYESSHEGSIIDVDRMKDIVKTCIESSLKSKIGASFSSVVQRDDLDPNFDMSAIVEMMIEDTSTDMFRCIAQRLEEDIKVSYDDAEFDKDDIDLFGPSHYREVTNLAMVSHPLMDKFVDHLVDKMGRKDLRRLISTCCVSEKNLDKAKLLFTFLQRDLSLIEVDSSEDELLSGSDSDGFI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KM042102
EMBL· GenBank· DDBJ
AIS25026.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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