A0A093YRV0 · A0A093YRV0_9PEZI

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site112L-glutamate (UniProtKB | ChEBI)
Active site387Nucleophile
Binding site405-407L-glutamate (UniProtKB | ChEBI)
Binding site429L-glutamate (UniProtKB | ChEBI)
Binding site457-458L-glutamate (UniProtKB | ChEBI)
Binding site480L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • ORF names
      V492_07025

Organism names

  • Taxonomic identifier
  • Strain
    • VKM F-4246
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Leotiomycetes incertae sedis > Pseudeurotiaceae > Pseudogymnoascus

Accessions

  • Primary accession
    A0A093YRV0

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-36
ChainPRO_500188965337-577Glutathione hydrolase

Interaction

Protein-protein interaction databases

Family & Domains

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    577
  • Mass (Da)
    62,328
  • Last updated
    2014-11-26 v1
  • Checksum
    48E34E2EF5274DC2
MHGFLGQANPGRSSNTRWRFALLSLLALLPPPSVEASIVLSRDGTRGAVASESSICSNIGIDLIRRGGNAADAAVGTTLCVGVIGMYHSGIGGGGFMLVRSETGEYEDVDFRETAPSAAYEDMYANFTIGSIVGGDASGVPGELRGFEYLHKKYGKLPWAMVVMPAAKVAERGFTVTEDLYGFMIGREKLGQYFLTEDPSWAMDFAPKGRLLQPGELMTRKRLGKTLRTIAKQGASAFYEGPIADATIRALQLANGSMTLDDMSKYEIITRKPVSIDYRGYKIFSTGAPSSGAVALNTFKIIEGYNMSDPDNLNLNTHRLDEAIKFSYGNRNELGDPDFVEGIADFQSQMLDTANASATRNKISDDHTLDPTAYNPKRLSHPDSHGTSHVVTSDASGLSITLTTTVNLSFGSRLCVPETGIIMNNEMNDFSIPGVSNEFGFVPSPNNYIRPGKRPLSSITPVIVEQADGSLYVVTGAAGGSRIITATIQALWHVLDHGMTMPEALAQPRLDDQLLPAQVRFELGYDNATTAYMRAKGHNVTWTSELLSKTQGIRRLENGTFEAAAEPRQKNSGGYAV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JPJU01002524
EMBL· GenBank· DDBJ
KFY07559.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp