A0A093YPS2 · A0A093YPS2_9PEZI

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per subunit.

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site259Mg2+ 1 (UniProtKB | ChEBI)
Binding site259Mg2+ 2 (UniProtKB | ChEBI)
Binding site263Mg2+ 1 (UniProtKB | ChEBI)
Binding site295Mg2+ 2 (UniProtKB | ChEBI)
Binding site299Mg2+ 2 (UniProtKB | ChEBI)
Binding site321substrate

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionketol-acid reductoisomerase activity
Molecular Functionmetal ion binding
Biological Processisoleucine biosynthetic process
Biological Processvaline biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ketol-acid reductoisomerase, mitochondrial
  • EC number
  • Alternative names
    • Acetohydroxy-acid reductoisomerase
    • Alpha-keto-beta-hydroxylacyl reductoisomerase

Gene names

    • ORF names
      V492_07542

Organism names

  • Taxonomic identifier
  • Strain
    • VKM F-4246
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Leotiomycetes incertae sedis > Pseudeurotiaceae > Pseudogymnoascus

Accessions

  • Primary accession
    A0A093YPS2

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain61-254KARI N-terminal Rossmann
Domain251-398KARI C-terminal knotted

Sequence similarities

Belongs to the ketol-acid reductoisomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    400
  • Mass (Da)
    44,530
  • Last updated
    2014-11-26 v1
  • Checksum
    63BA1C843BC8A249
MASRTLSRAARSQLARQFSAPVAKRTFVSAVNAATRPAVARAAAPVQQFRGVKTVDFAGDKEQVYERSDWPREKLLEYFKDDTLAMIGYGSQGHGQGLNARDQGLNVIVGVRKGGQSWREAEQDGWVEGKNLFDIDEAISRGTIIMNLLSDAAQSETWPHIKPQITKGKTLYFSHGFSPVFKELTKVDVPTDVDVILVAPKGSGRTVRTLFREGRGINASIAVYQDVTGKALEKSTALGVAVGAGYMYLTTFEKEVYSDLYGERGCLMGGIHGMFLAQYEVLREQGHSPSEAFNETVEEATQSLYPLIGANGMDWMYEACSTTARRGAIDWSSKFKDALKPVFNDLYDSVKTGKETQRSLDYNSQPDYREKYEAEMQEIRDLEIWRAGKAVRSLRPENQK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JPJU01002664
EMBL· GenBank· DDBJ
KFY06996.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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