A0A093VAT8 · A0A093VAT8_TALMA
- ProteinNAD(P)H-hydrate epimerase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids245 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
Catalytic activity
- (6R)-NADHX = (6S)-NADHX
Cofactor
Note: Binds 1 potassium ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 69-73 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
Binding site | 70 | K+ (UniProtKB | ChEBI) | |||
Binding site | 131 | K+ (UniProtKB | ChEBI) | |||
Binding site | 135-141 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
Binding site | 164 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
Binding site | 167 | K+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | metal ion binding | |
Molecular Function | NADHX epimerase activity | |
Molecular Function | NADPHX epimerase activity | |
Molecular Function | nucleotide binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD(P)H-hydrate epimerase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Trichocomaceae > Talaromyces > Talaromyces sect. Talaromyces
Accessions
- Primary accessionA0A093VAT8
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length245
- Mass (Da)26,996
- Last updated2014-11-26 v1
- ChecksumEEFB2F7A6E01B3D1
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JPOX01000032 EMBL· GenBank· DDBJ | KFX43821.1 EMBL· GenBank· DDBJ | Genomic DNA |