A0A093VAT8 · A0A093VAT8_TALMA

Function

function

Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: Binds 1 potassium ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site69-73(6S)-NADPHX (UniProtKB | ChEBI)
Binding site70K+ (UniProtKB | ChEBI)
Binding site131K+ (UniProtKB | ChEBI)
Binding site135-141(6S)-NADPHX (UniProtKB | ChEBI)
Binding site164(6S)-NADPHX (UniProtKB | ChEBI)
Binding site167K+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionmetal ion binding
Molecular FunctionNADHX epimerase activity
Molecular FunctionNADPHX epimerase activity
Molecular Functionnucleotide binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD(P)H-hydrate epimerase
  • EC number
  • Alternative names
    • NAD(P)HX epimerase

Gene names

    • ORF names
      GQ26_0320420

Organism names

  • Taxonomic identifier
  • Strain
    • PM1
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Trichocomaceae > Talaromyces > Talaromyces sect. Talaromyces

Accessions

  • Primary accession
    A0A093VAT8

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain19-225YjeF N-terminal
Domain47-132Rhodanese

Sequence similarities

Belongs to the NnrE/AIBP family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    245
  • Mass (Da)
    26,996
  • Last updated
    2014-11-26 v1
  • Checksum
    EEFB2F7A6E01B3D1
MSLKLQFNNDYQAISSKDAAALDKDLMDVGGFSLDQLMELAGISVSQAVYRFHPIRQGKNVLVVCGPGNNGGDGLVAARHLAHYGYKPSVYYPKEGKNELYQRLKIQLQNLDVTFVPDFTEALKSADLVVDGIFGFSFQKPLREPFPSIISQMEETKVPVLSIDAPSSWDIQEGPPKEGPGAKFMPGALISLTAPKPCVKWHRGRHFVGGRFLTKSIAEKYDIDIPDYPGVDQIIEIGVNADEKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JPOX01000032
EMBL· GenBank· DDBJ
KFX43821.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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