A0A093V6I2 · A0A093V6I2_TALMA

  • Protein
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular ComponentmRNA cleavage and polyadenylation specificity factor complex
Molecular Functionmyosin phosphatase activity
Molecular FunctionRNA polymerase II CTD heptapeptide repeat phosphatase activity
Biological ProcessmRNA processing
Biological Processtermination of RNA polymerase II transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72
  • EC number
  • Short names
    CTD phosphatase SSU72

Gene names

    • ORF names
      GQ26_0132300

Organism names

  • Taxonomic identifier
  • Strain
    • PM1
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Trichocomaceae > Talaromyces > Talaromyces sect. Talaromyces

Accessions

  • Primary accession
    A0A093V6I2

Proteomes

Subcellular Location

Keywords

  • Cellular component

Interaction

Subunit

Component of the cleavage and polyadenylation factor (CPF) complex.

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias23-39Polar residues
Region23-48Disordered

Sequence similarities

Belongs to the SSU72 phosphatase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    296
  • Mass (Da)
    33,047
  • Last updated
    2014-11-26 v1
  • Checksum
    A0AEAC9503381633
MATDPNPQLETVVVSNPEILSVTEADPSDSSQLTIPDPQLDDGSATPVTPAAAEAKGEESSYKLIFCTVCASNNNRSMEAHLQLSRSYPVISFGTGSLVRLPGPSITQPNVFNFDSTSYNHMYEDLYNKDQRLYRNNGILNMLDRNRNLKWGPERFQNWVPGQPRLDHIAKGDKGSLGTEAGVVDVIITCEERCWDAVVDDLLNRGSPLNRPVHVFNVDIRDNHEEALTGGKAIRDLADMLNAAANEERRLYDDPDAWDRGASEARQSFDEKVPEILGAWQEKYPNLPALWTLSWF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias23-39Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JPOX01000013
EMBL· GenBank· DDBJ
KFX48177.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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