A0A093BM47 · A0A093BM47_CHAPE

Function

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Note: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site186Proton donor
Binding site186-190AMP (UniProtKB | ChEBI)
Binding site190Zn2+ 1 (UniProtKB | ChEBI)
Binding site226Zn2+ 1 (UniProtKB | ChEBI)
Binding site227AMP (UniProtKB | ChEBI)
Binding site227Zn2+ 1 (UniProtKB | ChEBI)
Binding site227Zn2+ 2 (UniProtKB | ChEBI)
Binding site334AMP (UniProtKB | ChEBI)
Binding site334Zn2+ 1 (UniProtKB | ChEBI)
Binding site385AMP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function3',5'-cyclic-AMP phosphodiesterase activity
Molecular Function3',5'-cyclic-GMP phosphodiesterase activity
Molecular Functionmetal ion binding
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphodiesterase
  • EC number

Gene names

    • ORF names
      M959_10923

Organism names

  • Taxonomic identifier
  • Strain
    • M959
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Caprimulgimorphae > Apodiformes > Apodidae > Apodinae > Chaetura

Accessions

  • Primary accession
    A0A093BM47

Proteomes

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain109-486PDEase
Compositional bias483-530Basic and acidic residues
Region483-609Disordered
Compositional bias531-558Polar residues
Compositional bias559-609Basic and acidic residues

Sequence similarities

Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    609
  • Mass (Da)
    68,911
  • Last updated
    2014-11-26 v1
  • Checksum
    2C11274CBA79CF77
RLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDSVPSEVRDWLASTFTRQMGMMLKRTEEKPRFRSIVHAVQAGIFVERMYRRTSNMVGLSYPPAVIGVLKNVDKWSFDVFALNDASGDHALKFIFYELLTRYDLINRFKIPISALVSFVEALEVGYSKHKNPYHNLMHAADVTQTVHYLLFKTGVVHWLTELEIFAMIFAAAIHDYEHTGTTNNFHIQTRSDSAILYNDRSVLENHHVSAAYRLLQDDEEMNILSNLSKDDWREFRALVIEMVLATDMSCHFQQIKAMKNALQQPEGIDKPKALSLLLHTADISHPAKAWDLHHRWTMSLLEEFFRQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFTVLTDMTEKIVTPLIDEASRSGMSGFRRSSLNSISPSEVKRSSVKSTGSEGSASLNCSILTVDFKCFKATWTEVVQQNREKWKAQATKEEKAKKEAEENAHQGTDEKKTDEKDEKPSEDATAAKTENSKETNPGENRSADSNKSNVNGTQQTGVNKHEASQGKNTSRTDKGTDSHHSAGEEKQHVQNGELKEDNKLEKKDHSSVGDESKKTD

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias483-530Basic and acidic residues
Compositional bias531-558Polar residues
Compositional bias559-609Basic and acidic residues
Non-terminal residue609

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KN126477
EMBL· GenBank· DDBJ
KFU89953.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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