A0A089XP78 · A0A089XP78_9LACT
- ProteinAcetolactate synthase small subunit
- GeneilvN
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids158 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
Catalytic activity
- 2 pyruvate + H+ = (2S)-2-acetolactate + CO2
Pathway
Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | acetolactate synthase activity | |
Molecular Function | acetolactate synthase regulator activity | |
Biological Process | isoleucine biosynthetic process | |
Biological Process | valine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetolactate synthase small subunit
- EC number
- Short namesAHAS ; ALS
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Lactococcus
Accessions
- Primary accessionA0A089XP78
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Dimer of large and small chains.
Structure
Sequence
- Sequence statusComplete
- Length158
- Mass (Da)17,641
- Last updated2014-11-26 v1
- Checksum9A9D29AA5291A087
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAOQNN010000001 EMBL· GenBank· DDBJ | MCW2279663.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAOWLV010000001 EMBL· GenBank· DDBJ | MDG4975149.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAOWLP010000004 EMBL· GenBank· DDBJ | MDG4981103.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAOWLY010000012 EMBL· GenBank· DDBJ | MDG4984733.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAUCAE010000013 EMBL· GenBank· DDBJ | MDM7547216.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JARQDL010000003 EMBL· GenBank· DDBJ | MDT2945205.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
NCWV01000001 EMBL· GenBank· DDBJ | PAK90340.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MTJS01000002 EMBL· GenBank· DDBJ | PFG89238.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RAGV01000008 EMBL· GenBank· DDBJ | RQE32346.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
OGTW02000112 EMBL· GenBank· DDBJ | SPS12840.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
VJWV01000001 EMBL· GenBank· DDBJ | TRW75519.1 EMBL· GenBank· DDBJ | Genomic DNA |