A0A089VP72 · A0A089VP72_THAWE

Function

function

Acts as a processive, ATP-dependent zinc metallopeptidase.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

164050100150200250300350400450500550600
Type
IDPosition(s)Description
Binding site223-230ATP (UniProtKB | ChEBI)
Binding site444Zn2+ (UniProtKB | ChEBI); catalytic
Active site445
Binding site448Zn2+ (UniProtKB | ChEBI); catalytic
Binding site522Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentchloroplast thylakoid membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent peptidase activity
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processprotein catabolic process
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent zinc metalloprotease FtsH
  • EC number

Gene names

    • Name
      ftsH

Encoded on

  • Chloroplast

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Sar > Stramenopiles > Ochrophyta > Bacillariophyta > Coscinodiscophyceae > Thalassiosirophycidae > Thalassiosirales > Thalassiosiraceae > Conticribra

Accessions

  • Primary accession
    A0A089VP72

Subcellular Location

Membrane
Plastid, chloroplast thylakoid membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane126-148Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-24
ChainPRO_503000279825-640ATP-dependent zinc metalloprotease FtsH

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain215-354AAA+ ATPase

Sequence similarities

Belongs to the AAA ATPase family.
In the C-terminal section; belongs to the peptidase M41 family.
In the N-terminal section; belongs to the AAA ATPase family.
In the central section; belongs to the AAA ATPase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    640
  • Mass (Da)
    69,843
  • Last updated
    2014-11-26 v1
  • Checksum
    210BF9C64FC45107
MGQQILRALLIGLILISIIDLSVKTFGIESPESPDTIRNQTQLNQNVVSSRMTYGRFLEYLEMGWVKQVDLYDNSRNAIVQASSPELGNRPQTIRVEIPVGASQLIQKLKEYNIDFDAHPAEQKNLFVTVASNLLLPLVFIAGLVYFFQNSESFGGGSGQSPLSLGKSTARFERRPDTGVNFNDIAGIDEAKAEFEEIVSFLKEPEKYTVVGAKIPKGILLVGPPGTGKTLLAKAIANEADVPFFSVAGSEFVEMFIGIGAARVRDLFQKASENAPCIVFIDEIDAVGRERGAGVGGGNDEREQTLNQLLTEMDGFKENKGVIVVGATNRVDILDAALLRPGRFDRQVTVNLPDRLGRISILKVHAKNKPLGEDVSLVQLANRTPGFSGADLANLLNEAAILATRYKKTTISKNEVNQAIDRIIGGIAGTPMEDSKNKKLIAYHEVGHAITGTVLQSHDEVEKITITPRGAAKGLTWFTPEEDQTLISRSALLARIIGTLGGRAAEQVIFGDPEVTTGASSDLQQVTNLARQMVTRFGMSNIGPIALEDESNGQVFLGGMTQDSEYPESIADRIDDEVCKIINYCEQKALQIILDNRVIIDLVIEKLLDVETMEGDEFRELLSTYTVLPNKKAAYVSKFS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KJ958485
EMBL· GenBank· DDBJ
AIR76125.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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