A0A089VP72 · A0A089VP72_THAWE
- ProteinATP-dependent zinc metalloprotease FtsH
- GeneftsH
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids640 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Acts as a processive, ATP-dependent zinc metallopeptidase.
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 223-230 | ATP (UniProtKB | ChEBI) | |||
Binding site | 444 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 445 | ||||
Binding site | 448 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 522 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast thylakoid membrane | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATP-dependent peptidase activity | |
Molecular Function | metalloendopeptidase activity | |
Molecular Function | zinc ion binding | |
Biological Process | protein catabolic process | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent zinc metalloprotease FtsH
- EC number
Gene names
Encoded on
- Chloroplast
Organism names
- Taxonomic lineageEukaryota > Sar > Stramenopiles > Ochrophyta > Bacillariophyta > Coscinodiscophyceae > Thalassiosirophycidae > Thalassiosirales > Thalassiosiraceae > Conticribra
Accessions
- Primary accessionA0A089VP72
Subcellular Location
UniProt Annotation
GO Annotation
Plastid, chloroplast thylakoid membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 126-148 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-24 | ||||
Chain | PRO_5030002798 | 25-640 | ATP-dependent zinc metalloprotease FtsH | ||
Interaction
Subunit
Homohexamer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 215-354 | AAA+ ATPase | |||
Sequence similarities
Belongs to the AAA ATPase family.
In the C-terminal section; belongs to the peptidase M41 family.
In the N-terminal section; belongs to the AAA ATPase family.
In the central section; belongs to the AAA ATPase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length640
- Mass (Da)69,843
- Last updated2014-11-26 v1
- Checksum210BF9C64FC45107
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KJ958485 EMBL· GenBank· DDBJ | AIR76125.1 EMBL· GenBank· DDBJ | Genomic DNA |