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A0A087X009 · A0A087X009_HUMAN

  • Protein
    ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
  • Gene
    ABO
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mn2+ ion per subunit.

Features

Showing features for binding site, active site.

137350100150200250300350
Type
IDPosition(s)Description
Binding site120-122UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site125UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site210Mn2+ (UniProtKB | ChEBI)
Binding site210-212UDP-N-acetyl-alpha-D-galactosamine (UniProtKB | ChEBI)
Binding site212Mn2+ (UniProtKB | ChEBI)
Binding site232an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Binding site244an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Active site302Nucleophile
Binding site302an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)
Binding site325an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionhexosyltransferase activity
Molecular Functionmetal ion binding
Biological Processcarbohydrate metabolic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

Gene names

    • Name
      ABO

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A087X009

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-37Helical

Keywords

  • Cellular component

Disease & Variants

Variants

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The viewer provides 491 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Expression

Gene expression databases

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 6 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    373
  • Mass (Da)
    42,938
  • Last updated
    2014-10-29 v1
  • MD5 Checksum
    AE2042B859F84641A1D82E34AEFBCF53
MAEVLRTLAGKPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERGFCMAVREPDHLQRVSLPRMVYPQPKVLTPCRKDVLVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRRERLPGALGGLPAAPSPSRPWF

Computationally mapped potential isoform sequences

There are 6 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P16442BGAT_HUMANABO354
A0AAG2UWH5A0AAG2UWH5_HUMANABO61
A0A7P0TA91A0A7P0TA91_HUMANABO23
A0A087X0C2A0A087X0C2_HUMANABO353
W6JLF7W6JLF7_HUMANABO354
A0AAG2TLY5A0AAG2TLY5_HUMANABO79

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL732364
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AL772161
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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