A0A087WV01 · A0A087WV01_HUMAN
- ProteinElongation factor 1-alpha
- GeneEEF1A1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids426 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | translation elongation factor activity |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameElongation factor 1-alpha
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A087WV01
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 398 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | ||
---|---|---|---|---|---|---|
Modified residue (large scale data) | 6 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 18 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 21 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 22 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 23 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 24 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 29 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 85 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 86 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 141 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 142 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 162 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 175 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 177 | PRIDE | Phosphotyrosine | |||
Modified residue (large scale data) | 224 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 226 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 227 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 239 | PRIDE | Phosphothreonine | |||
Modified residue (large scale data) | 289 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 298 | PRIDE | Phosphoserine | |||
Modified residue (large scale data) | 394 | PRIDE | Phosphoserine | |||
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 5-242 | Tr-type G | |||
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length426
- Mass (Da)46,360
- Last updated2014-10-29 v1
- MD5 Checksum653F680CB7441BEE80854B2DE66E1962
Computationally mapped potential isoform sequences
There are 7 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P68104 | EF1A1_HUMAN | EEF1A1 | 462 | ||
Q5JR01 | Q5JR01_HUMAN | EEF1A1 | 145 | ||
A6PW80 | A6PW80_HUMAN | EEF1A1 | 106 | ||
A0A087WVQ9 | A0A087WVQ9_HUMAN | EEF1A1 | 459 | ||
A0A7I2V3H3 | A0A7I2V3H3_HUMAN | EEF1A1 | 376 | ||
A0A7I2V5N4 | A0A7I2V5N4_HUMAN | EEF1A1 | 433 | ||
A0A7I2V659 | A0A7I2V659_HUMAN | EEF1A1 | 459 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL603910 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |